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80575 tn?1207132364

'Wild Type' and 'Resistant' virus

Sorry to post twice in one day...I have HCV on my mind today.

Lately I've read several articles about studies involving "wild type" virus and/or "resistant" virus.  Most articles were about the new p.i.'s coming out.  

My question is does anyone have a definitions for these terms?  Am I mistaken but under tx does this mean that the virus mutates into a different form?

I'd appreciate hearing what you guys know.  

3 Responses
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Avatar universal
This was helpful to me i explaining some of the mechaisms of this virus.

http://vir.sgmjournals.org/cgi/content/full/85/11/3173
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80575 tn?1207132364
Yikes!  Thanks for the link, there's a lot of data there that I'll go over this evening.
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Avatar universal
I didn't read the link above, and just posting quickly, but wild-type is typically referred to the virus we carry, resistant strains of course are related to the tx.
resistant strains can also be called less-fit, meaning even though they developed, they  might not have the potency they should.
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