Hepatitis C Community
about my lap results
About This Community:

This forum is for questions about medical issues and research aspects of Hepatitis C such as, questions about being newly diagnosed, questions about current treatments, information and participation in discussions about research studies and clinical trials related to Hepatitis. If you would like to communicate with other people who have been touched by Hepatitis, please visit our new Hepatitis Social/Living with Hepatitis forum

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

about my lap results

i received this information from my liver biopsy i need help understanding what it means .


--Final Pathologic Diagnosis---

A. Liver, needle core biopsy:
- Chronic hepatitis with mild activity (grade 2 of 4), portal and
focal periportal fibrosis (stage 2 of 4), consistent with viral Hepatitis
C; see note.
- Minimal macrovesicular steatosis.
Note: The liver needle biopsy has greater than 10 portal tracts
available for evaluation. The hepatic architecture is intact. The portal
areas are expanded by a mild predominantly lymphocytic infiltrate with
admixed histiocytes, occasional neutrophils, eosinophils, and rare plasma
cells. The hepatic artery and portal vein are present and intact. Bile duct
branches are present with no evidence of duct damage. No proliferating bile
ductules are identified at the interface. Mild interface hepatitis is
present in many portal areas with inflammation extending into the lobule.
The lobular parenchyma shows a minimal large and small droplet
macrovesicular steatosis and scattered small clusters of inflammatory
infiltrate. Rare dead hepatocytes are seen. No hepatocytes ballooning or
Mallory-Denk bodies are identified in hepatocytes. Cholestasis is not
present. Central areas and vessels appear unremarkable. A trichrome stain
shows portal and periportal fibrosis with focal pericellular fibrosis and
portal to portal thin bridging. An iron stain does not show iron deposition
within hepatocytes or Kupffer cells.
1747881_tn?1358189534
Basically what it is saying is that you have moderate liver damage, you are grade 2, stage 2.

Grading & Staging a Liver Biopsy

Metavir

The Metavir scoring system was specially designed for patients with hepatitis C.  The scoring consists of using a grading and a staging system.  The grade gives an indication of the activity or amount of inflammation and the stage represents the amount of fibrosis or scarring.  
The grade is assigned a number based on the degree of inflammation, which is usually scored from 0-4 with 0 being no activity and 3 or 4 considered severe activity.  The amount of inflammation is important because it is considered a precursor to fibrosis.  

The fibrosis score is also assigned a number from 0-4:
• 0 = no scarring
• 1 = minimal scarring
• 2 = scarring has occurred and extends outside the areas in the liver that contains blood vessels
• 3=bridging fibrosis is spreading and connecting to other areas that contain fibrosis
• 4=cirrhosis or advanced scarring of the liver

www.hcvadvocate.org/hepatitis/factsheets_pdf/grade_stage.pdf
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Hepatitis C Community Resources
RSS Expert Activity
233488_tn?1310696703
Blank
New Cannabis Article from NORTH Mag...
Jul 20 by John C Hagan III, MD, FACS, FAAOBlank
242532_tn?1269553979
Blank
3 Reasons Why You are Still Binge E...
Jul 14 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Emotional Eating: What Your Closet ...
Jul 09 by Roger Gould, M.D.Blank
Top Hepatitis Answerers
Avatar_f_tn
Blank
dontworry_behappy1
163305_tn?1333672171
Blank
orphanedhawk
Rural Mural, CA
Avatar_f_tn
Blank
nan535
Brooklyn, NY
446474_tn?1404424777
Blank
HectorSF
CA
1815939_tn?1377995399
Blank
pooh55811
96938_tn?1189803458
Blank
FlGuy
South, FL