SAN FRANCISCO, Nov. 4 -- Hepatitis C-positive liver transplant recipients live just as long whether the donor is HCV-positive or -negative, data from the national transplant network suggest.
HCV-positive organ recipients lived an average of 8.28 years after receiving a liver from an HCV-positive donor, Patrick G. Northrup, M.D., of the University of Virginia in Charlottesville, reported here at the annual meeting of the American Association for the Study of Liver Diseases.
After adjustment for known mortality risks associated with HCV, the survival did not differ from the 10-year mean among HCV-positive patients who received livers from HCV-negative donors.
"It looks like recipients with hepatitis C can receive an organ from someone with the hepatitis C antibodies and do as well as they would with a non-hepatitis C donor," said Dr. Northrup. "That's with careful patient selection."
The need for donor livers far exceeds the supply, and extended-criteria donor selection has offered a partial solution to the organ shortage, Dr. Northrup noted. Use of HCV-positive grafts for HCV-positive patients offers an example of marginal-donor expansion.
Cirrhosis secondary to HCV infection has accounted for as many as half of all liver transplants performed in the U.S., and more than four million people are currently infected, Dr. Northrup continued.
The issue of transplanting organs from HCV-positive donors has particular relevance in that population of liver transplant patients, he said, but the long-term consequences and outcomes had not been carefully studied.
no, if you have a SVR you have a Sustained Viral Response, which means your virus is no longer detectable. You will always have the antibodies of the virus, its like once you have had the chicken pox you still have the antibodies even though you no longer have the chicken pox themselves. So no you never can donate blood or organs.
You can donate organs!!!!!!!!!!!!!!!! Not blood.
Can-do and Will have it right.
With the HCV+organs it is a decision that the transplant team/surgeon makes with the organ recipient.
Generally HCV+ organs go to HCV+ recipients but they could go to a HCV negative recipient in the right situation.
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