The interval of 3 years may be inadequate to measure disease progression. This progression seems to accelerate in later stages which is why I asked what stage you were at. I've heard some say biopsy every 2 years if the liver shows advanced stages of disease. The longer you have the disease, the more fibrosis develops and once we reach a certain age liver disease starts advancing more quickly. It can take many many years to reach stage 3 but after that it starts to accelerate and you can go from stage 3 to stage 4 between 3-5 years. Age also plays a role in how quickly the damage can advance.
Here's an example, I'm old and I think I'm rotting rather quickly. lol I had my first in 2003, my second in 2005 and my last 10/08, I'll be 55 this month and for this Boceprevir trial I'm starting they required that your bx not be older than 18 months. Trinity is right on spot.
Is there a change in the stage after treatment? I would assume the grade would be the same as that is damage.... Has anyone had a biopsy after? I am scheduled for one but not sure if I neeeed to do it.
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