can any 1 help me

[fawadnasrullah]

Hi
i get exposed to blood of HCV positive person (on the open fresh wound of scratches at my foot) about 7 weeks ago. i did my  ELISA for HCV antibodies abut 7 days later and it was negative but after this my liver enzymes started rising my ALT reached to the level of 160 at the end of third week
at that time (3 weeks after exposure) i went for qualitative pcr for HCV and it was negative and my ELISA was negative too. i went for repeat ELISA and LFTs at the end of month and my Elisa was negative and ALT downs to 52 (control 42)
NOW AT THE END OF SEVENTH WEEK I AGAIN REPEATED MY ELISA AND LFTs. my alt is still 52 but this time my ELISA is positive.controll is 1 and my value is 1.8.
Tomorrow i have time for repeat pcr
Can u please tell me that now i had Hepatitis confirmed?

[Bill1954]

A positive HCV RIBA result indicates that exposure actually occurred, vs. a false positive antibody result. Of course, after exposure, 15% of patients will still clear the virus spontaneously with their own immune response.

In early, acute infection HCV RNA is often intermittent; this might explain the negative PCR result.

I agree with others; retest with PCR, perhaps at 30 days post exposure. If positive, it might be a good idea to treat the HCV as an acute infection; this yields high rates of long term success.

Good luck—

Bill

[carol411]

Since you had a PCR at three weeks, you probably do not have hep c.  If hep c were in your blood it should show up at two weeks post exposure.  Something is going on though.  I think you will be fine, especially if the scratches on your foot had scabbed over.  Hep c is not the only condition that would effect ALT.  And for some people antibodies take a while to build up.  Your ELISA was too soon after exposure to be trusted.  If you plan on taking another PCR tomorrow that result should let you know one way or the other.  There has been plenty of time since exposure for the test give accurate results.  Good luck.  I hope you are fine.

[nygirl7]

It's doubtful you are positive but get the PCR and be done with it. No one here can know for sure what is going on and all we can do is guess. The PCR will tell you if you have the virus or not.

Get tested.

[Diane12855]

I have read that it can take some time for out body to produce antibodies so this scenario is possible. To be certain, you need to have a viral load done... right now my brain fog refuses to give up the name of that test... anyhow, that will check for the actual virus in your blood. It will come back either undetectable or with the amount of virus in the sample.

Good luck,

Diane