elevated AST

I started Pegintrol / Ribavirin treatment in Septembe of 06 My ALT has always remained slightly elevated by 5 to 10 point out of range & my AST has always been normal. Just this month my ALT went from being 50 to 120 & my AST went from 35 to 70. I had a live biopsy about 5 years ago & they said I had no fibrosis just mild inflamation (inflammation) due to cronic (chronic) HCV. Should I now be concerned? My Doc say's not to worry we will check agian. This is my second attempt to know out the HCV.

Thank you

[wndycity]

I had a similar experience in that my ALT and AST were 54 and 47 respectively before treatment, down to 26 and 30 during the 15 months that I was on treatment (did not repsond) and spiked up to 185 and 121, three months after treatment. My other blood panel numbers were normal and my doc, who I pressed on this issue a couple of times, was not worried and expected this would settle back down.

I hope this helps.

[ladybug52]

Also AST is not as liver specific as AlT. Just quoting JMJM.
He's much more knowledgeable and maybe will post something tomorrow.

[ladybug52]

What was your last pcr re: viral load? Are you still treating? I have heard others say they have not had lowered liver enzymes during tx. Guess it's an individual thing.

[canuckle9]

My enzymes spiked after week 14 of tx. my PCR was one million sixhundred thousand & at 12 weeks it came down one copy (three hundred thousand)

thank you