Aa
geno 2B cirrhosis
Hello - my husband is geno 2B and is doing peg/riba combination.
He was diagnosed with Hep C when he had his gall bladder removed. At that time we found out that he has stage 4 cirrhosis. My husband has been sober for 22 years - I am sure that he would not be with me if he were drinking. .
Before treatment he had a viral load of 8,000,000 - at week 4 it was 800,000. The doctor warned us that the treatment might not be as effective given his cirrhosis. I watch him for signs of selling but he seems fine. I am reading with interest about the vitamin D and am wondering if you think that it would help his chances with the treatment. He is getting tested again at week 12. Other than minor fatigue, he has had few side effects
I would love to hear from people out there who might some comments or suggestions.
He was diagnosed with Hep C when he had his gall bladder removed. At that time we found out that he has stage 4 cirrhosis. My husband has been sober for 22 years - I am sure that he would not be with me if he were drinking. .
Before treatment he had a viral load of 8,000,000 - at week 4 it was 800,000. The doctor warned us that the treatment might not be as effective given his cirrhosis. I watch him for signs of selling but he seems fine. I am reading with interest about the vitamin D and am wondering if you think that it would help his chances with the treatment. He is getting tested again at week 12. Other than minor fatigue, he has had few side effects
I would love to hear from people out there who might some comments or suggestions.
Thank you for all your responses. I am not sure whether or not his liver is compensated or decompensated. I will ask he doctor next week. We go to a G/I who has a large number of patients with Hep C. She seems to know what she was doing and was ready to refer hum out according to his levels - which all seem to be pretty good.. He is on a pretty low dose of riba - 800 per day (400 per dose).
Forgive any typos
Forgive any typos
Welcome to the group..
Inregars to your question about Vit. D:
Studies have shown that approx. 60% of people with HCV are either Vitimin D deficient or have insufficient amounts when measured.
The normal reference range is 30 -100 ng/dl
The message seems to be that adequate levels should be monitored for as it "may"be of a benefit for general health and possibly improved treatment response.
Vit D however is a fat soluble vitamin and stored in the liver ,therefore excessive amounts could be harmful.
Seems like everything else...moderation to insure adequate levels is best..
.I was tested for Vit D when I started tx. and was slightly deficient and my hepatologist put me on 2000 per day while treating ,,which I still take and my level is maintained at 40ng/dl.
Will
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950664/
G&H What research is needed with regard to vitamin D deficiency associated with liver disease?
SN As noted above, clinicians and patients need to be more aware of the potential for and risks of vitamin D deficiency. Current research needs include evaluating the role of vitamin D supplementation to enhance treatment response among patients with hepatitis C and the role of actin-free vitamin D binding protein in hepatocellular carcinoma. In addition, it is important for us to learn the optimal duration and dose of vitamin D replacement for patients with liver failure.
G&H Should patients with liver disease be monitored for vitamin D deficiency?
SN Yes. All hepatologists should monitor vitamin D levels and treat deficient patients. The goal for all patients with chronic liver disease should be a 25-OH vitamin D level of 30 ng/mL. Anything less than 15–20 ng/mL is considered deficiency.
G&H Has vitamin D deficiency always been a problem for people with liver disease, or has this been changing recently?
SN It is likely that it was always a problem, but the data from the National Health and Nutrition Examination Survey indicate that the mean serum level of 25-OH vitamin D has decreased over the last 2 decades. It may be that the more severe vitamin D deficiency is only now coming to light.
Inregars to your question about Vit. D:
Studies have shown that approx. 60% of people with HCV are either Vitimin D deficient or have insufficient amounts when measured.
The normal reference range is 30 -100 ng/dl
The message seems to be that adequate levels should be monitored for as it "may"be of a benefit for general health and possibly improved treatment response.
Vit D however is a fat soluble vitamin and stored in the liver ,therefore excessive amounts could be harmful.
Seems like everything else...moderation to insure adequate levels is best..
.I was tested for Vit D when I started tx. and was slightly deficient and my hepatologist put me on 2000 per day while treating ,,which I still take and my level is maintained at 40ng/dl.
Will
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950664/
G&H What research is needed with regard to vitamin D deficiency associated with liver disease?
SN As noted above, clinicians and patients need to be more aware of the potential for and risks of vitamin D deficiency. Current research needs include evaluating the role of vitamin D supplementation to enhance treatment response among patients with hepatitis C and the role of actin-free vitamin D binding protein in hepatocellular carcinoma. In addition, it is important for us to learn the optimal duration and dose of vitamin D replacement for patients with liver failure.
G&H Should patients with liver disease be monitored for vitamin D deficiency?
SN Yes. All hepatologists should monitor vitamin D levels and treat deficient patients. The goal for all patients with chronic liver disease should be a 25-OH vitamin D level of 30 ng/mL. Anything less than 15–20 ng/mL is considered deficiency.
G&H Has vitamin D deficiency always been a problem for people with liver disease, or has this been changing recently?
SN It is likely that it was always a problem, but the data from the National Health and Nutrition Examination Survey indicate that the mean serum level of 25-OH vitamin D has decreased over the last 2 decades. It may be that the more severe vitamin D deficiency is only now coming to light.
Welcome to the forum, and i wish your husband the best of luck. It would be best to first find out from his doctor if he needs more before taking it.
Good luck.
Good luck.
Is his cirrhosis compensated? If it is decompensated, he has less chance of succeeding.
Of course he should be taking vitamin D, not only to help him with the treatment but to protect his bones, which tx is hard on.
The good thing is he is genotype 2. The bad thing is he has cirrhosis.
How long has he been on treatment? If it's less than 8 weeks, I'd suggest an 8 week viral load, rather than waiting until 12 weeks.
Due to his cirrhosis it might be advisable for him to extend treatment beyond the normal 24 weeks for genotype 2.
Hopefully he has a good liver doctor working with him who can advise him on his options.
Of course he should be taking vitamin D, not only to help him with the treatment but to protect his bones, which tx is hard on.
The good thing is he is genotype 2. The bad thing is he has cirrhosis.
How long has he been on treatment? If it's less than 8 weeks, I'd suggest an 8 week viral load, rather than waiting until 12 weeks.
Due to his cirrhosis it might be advisable for him to extend treatment beyond the normal 24 weeks for genotype 2.
Hopefully he has a good liver doctor working with him who can advise him on his options.
Someone else just posted a similar question about Vitamin D.. http://www.medhelp.org/posts/Hepatitis-C/Vitamin-D-and-Hep-C-Treatment/show/1678676 .. Lot's of responses.. Hope this helps..
Have an Answer?
You are reading content posted in the Hepatitis C Community
Learn about this treatable virus.
Getting tested for this viral infection.
3 key steps to getting on treatment.
4 steps to getting on therapy.
What you need to know about Hep C drugs.
How the drugs might affect you.
These tips may up your chances of a cure.
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.
