Hemolytic anemia is a common side effect of Ribavirin. (hemoglobin <10 g/dL)
Just like a car, your body needs fuel to run. Hemoglobin, or Hb, is important because it transports oxygen in your blood to all parts of your body. Think of the oxygen carried by hemoglobin as the fuel your body needs to stay alive and run efficiently. Hemoglobin is a substance found in your red blood cells that carries most of your oxygen. Although other substances in your body, such as water and plasma, also carry oxygen,
hemoglobin is unique because it can carry four times as much oxygen throughout the body.
Anemia is caused by low levels of red blood cells, or hemoglobin, in your blood. A severely anemic person’s blood cannot carry enough oxygen to meet the needs of the body tissues. As a result, over time the person becomes tired physically and mentally, and feels cold. When on interferon and ribavirin treatment for Hepatitis C, a
reduction in hemoglobin very commonly occurs and in most cases, it is maintained at levels below the normal laboratory ranges, returning to normal after treatment is completed or stopped. Anemia is an expected side effect of treatment with interferon and ribavirin.
Heart attacks are the most server side effect of Ribavirin due to anemia. Cardiac disease may be worsened by drug induced anemia, patients with a history of 274 significant or unstable cardiac disease should not use Ribavirin.
For safety information about Ribavirin and PegINF go to MedWatch: The FDA Safety Information and Adverse Event Reporting Program.
My understanding is that the brain gets the oxygen first, so it's the other parts of the body that tend to suffer most in cases of anemia. Thank goodness tx anemia doesn't sacrifice brain cells -- otherwise, as anemic as my husband has been on treatment, he'd probably have forgotten his own name by now! ~eureka
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.