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hep c drug trials
I was wondering if someone would know where I could find information on drug trials in pa.I finished a trial back inJune with no success.My trial nurse told me then that another one would be starting again for relapsers in the spring.Now she called me and said she isnt sure if they are going to be starting another trial.I would like to look for another hospital that may be starting a trial.i dont mind traveling for the chance to beat this thing.I live in the Harrisburg,Pa area.Any help would be greatly appreciated.
thank you for all your suggestions.And Bill thank you,i am looking over some trials that are on the websight that you suggested for me.However since I have learned that Teleprevir may be released soon,I have to decide if I should wait for that.I am a stage 2 right now.So it isnt an emergency,but I would like to treat as soon as possible again.It is still a big disappointment that I relapsed when everyone including me thought I had it beat.I am going to call my doctor this week and talk to her about Teleprevir.
Your question was if someone could help you locate a trial in your particular area,and I believe Bill has given you a good starting point in that regard,also Trinity brings up a good point about wheather or not in your previous trial you were taking a protease inhibitor ,as you could run into resistance issues.
As far as,why would you want to enter a trial at this point(even though you hadn"t asked that question)there could be many reasons,1)if after researching available data on the study drug,and it has had good effects thus far in its progression and there is a high percentage chance of receiving the drug during the trial,you may want to take the chance of treating now with what will be available only in the future,and when that is at this point is uncertain.2) for the most part you receive very good care and monitoring.3) the treatment is usually looked after financially also4) your stage of fibrosis may be at a point you don"t feel comfortable waiting for the new meds.
Just some points to consider...always a personal decision
WILL
As far as,why would you want to enter a trial at this point(even though you hadn"t asked that question)there could be many reasons,1)if after researching available data on the study drug,and it has had good effects thus far in its progression and there is a high percentage chance of receiving the drug during the trial,you may want to take the chance of treating now with what will be available only in the future,and when that is at this point is uncertain.2) for the most part you receive very good care and monitoring.3) the treatment is usually looked after financially also4) your stage of fibrosis may be at a point you don"t feel comfortable waiting for the new meds.
Just some points to consider...always a personal decision
WILL
I forgot to mention that some clinical trials do not alllow rescue drugs so you are forced to reduce the peg and riba dose and therefore decrease your chances of clearing the virus.
My question is why would you want to do a trial at this point?
If you have not been treated with Teleprevir, it is very likely that it will come out this year.If you are not in a trial you can do some other things that might help along with the Teleprevir.
Predose Riba.
Add Vit D.
Take your first 7 shots of Peg 5 days apart rather than 7 days apart.
There are clinical studies that show a little more success in all of these so why not try them together? You could do these on your own but maybe not while in a trial.
If you have not been treated with Teleprevir, it is very likely that it will come out this year.If you are not in a trial you can do some other things that might help along with the Teleprevir.
Predose Riba.
Add Vit D.
Take your first 7 shots of Peg 5 days apart rather than 7 days apart.
There are clinical studies that show a little more success in all of these so why not try them together? You could do these on your own but maybe not while in a trial.
Did your previous trial include a protease inhibitor? If so, resistance develops and subsequent treatment with a protease inhibitor would be ineffective. However, if a polymerase inhibitor was used no resistance and you could treat with a protease or another polymerase or both.
Trinity
Trinity
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Have you looked through the clinicaltrials.gov site yet?
If you enter ‘HCV + your location’ in their search engine, you should come up with some options; assuming something is available at this time.
I tried Harrisburg HCV and only one entry was listed; here’s the site; you might want to fiddle with location and see what you come up with:
http://clinicaltrials.gov/ct2/results?term=harrisburg+hcv
If you come across something that looks interesting, reference the trial by NTC number in here (it will look something like this: NCT00456248), and perhaps someone will help you sort out the details.
Good luck—
--Bill