Hepatitis C Community
hepatitis c and corticosteroids
About This Community:

This forum is for questions about medical issues and research aspects of Hepatitis C such as, questions about being newly diagnosed, questions about current treatments, information and participation in discussions about research studies and clinical trials related to Hepatitis. If you would like to communicate with other people who have been touched by Hepatitis, please visit our new Hepatitis Social/Living with Hepatitis forum

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

hepatitis c and corticosteroids

i have a 55 year old patient with hepatitic c that is only 4 weeks into interon treatment ( on renal replacement therapy i.e HD ) , that has developed decreased hearing in both ears , the ENT specialist soes not think its related to treatment and has adviced a short course of oral steroids . my questions are
1) any link between the hearing loss and interferon in the literature ?
2) how safe is it give him oral steroids at this stage ?
3) is it beneficial to use viral load or liver enzymes as a guide to decide on treatment with steroids ?
Related Discussions
5 Comments Post a Comment
Blank
Avatar f tn
It would be wise for your ENT to consult with your hepatologist or doctor who is supervising your hepc treatment and perhaps your Nephrologist to see what your best course of action is.

I've have read where tinnitus (ringing in the ears) has resulted from the the hepc treatment drugs and even a few posts stating they have experienced diminished hearing while on treatment but once treatment ended hearing was restored to normal.  
Steroids are known to suppress the immune system but they're quite remarkable when needed to reduce inflammation and assist in alleviating respiratory problems. I could not advise if a short course of steroids would be safe at this juncture but certainly your hep doc could.

Trinity
Blank
Avatar m tn
There are no doctors on here, we're all patients :-) Just so we're clear.

Blank
717272 tn?1277594380
There are case studies on the internet about interferon-induced hearing loss.  Patients were usually treated with steroids (immune suppression) after stopping interferon (immune amplification) and hearing was restored.  Some patients continue interferon therapy and the hearing loss clears on it's own but some don't recover.  Do a search with the terms interferon and hearing loss to find those case-studies.

Another approach is to do intratympanic injections with corticosteroids.  The injections allow local application of corticosteroids rather than oral.  You can read more on this topic at http://emedicine.medscape.com/article/857511-print
The treatment is done by an otolaryngologist specialized in procedures and is expensive in the US, about $1500.
Blank
Post a Comment
To
Recent Activity
406584 tn?1399591666
Blank
10356 Coyote is always out there ... Comment
2 hrs ago
18227105 tn?1463525612
Blank
JesusSon commented on pitter's status
4 hrs ago
317787 tn?1463415842
Blank
Dee1956 commented on Belle313's status
May 27
Blank
Weight Tracker
Track your weight over time
Start Tracking Now
Top Hepatitis Answerers
683231 tn?1438659664
Blank
Auburn, WA
446474 tn?1446351282
Blank
San Francisco, CA
163305 tn?1333672171
Blank
Rural Mural, CA
1815939 tn?1377995399
Blank
Avatar universal
Blank
317787 tn?1463415842
Blank
DC
Hepatitis C Community Resources