Hepatitis C Community
hepatitis c and corticosteroids
About This Community:

This forum is for questions about medical issues and research aspects of Hepatitis C such as, questions about being newly diagnosed, questions about current treatments, information and participation in discussions about research studies and clinical trials related to Hepatitis. If you would like to communicate with other people who have been touched by Hepatitis, please visit our new Hepatitis Social/Living with Hepatitis forum

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

hepatitis c and corticosteroids

i have a 55 year old patient with hepatitic c that is only 4 weeks into interon treatment ( on renal replacement therapy i.e HD ) , that has developed decreased hearing in both ears , the ENT specialist soes not think its related to treatment and has adviced a short course of oral steroids . my questions are
1) any link between the hearing loss and interferon in the literature ?
2) how safe is it give him oral steroids at this stage ?
3) is it beneficial to use viral load or liver enzymes as a guide to decide on treatment with steroids ?
Related Discussions
5 Comments Post a Comment
Blank
Avatar f tn
It would be wise for your ENT to consult with your hepatologist or doctor who is supervising your hepc treatment and perhaps your Nephrologist to see what your best course of action is.

I've have read where tinnitus (ringing in the ears) has resulted from the the hepc treatment drugs and even a few posts stating they have experienced diminished hearing while on treatment but once treatment ended hearing was restored to normal.  
Steroids are known to suppress the immune system but they're quite remarkable when needed to reduce inflammation and assist in alleviating respiratory problems. I could not advise if a short course of steroids would be safe at this juncture but certainly your hep doc could.

Trinity
Blank
Avatar m tn
There are no doctors on here, we're all patients :-) Just so we're clear.

Blank
717272 tn?1277594380
There are case studies on the internet about interferon-induced hearing loss.  Patients were usually treated with steroids (immune suppression) after stopping interferon (immune amplification) and hearing was restored.  Some patients continue interferon therapy and the hearing loss clears on it's own but some don't recover.  Do a search with the terms interferon and hearing loss to find those case-studies.

Another approach is to do intratympanic injections with corticosteroids.  The injections allow local application of corticosteroids rather than oral.  You can read more on this topic at http://emedicine.medscape.com/article/857511-print
The treatment is done by an otolaryngologist specialized in procedures and is expensive in the US, about $1500.
Blank
Post a Comment
To
Recent Activity
317787 tn?1465993311
Blank
Dee1956 commented on No Cirrhosis of the L...
15 mins ago
707563 tn?1455827280
Blank
Emily_MHModerator Survey link - https://goo.g... Comment
13 hrs ago
3197167 tn?1348972206
Blank
clean_in_ks commented on No Cirrhosis of the L...
14 hrs ago
Blank
Weight Tracker
Track your weight over time
Start Tracking Now
Top Hepatitis Answerers
163305 tn?1333672171
Blank
Rural Mural, CA
1815939 tn?1377995399
Blank
446474 tn?1446351282
Blank
San Francisco, CA
Avatar universal
Blank
317787 tn?1465993311
Blank
DC
1747881 tn?1358189534
Blank
Greeley, CO
Hepatitis C Community Resources
RSS Expert Activity
233488 tn?1310696703
Blank
Marathon Running Done Over Many Yea...
05/15 by John C Hagan III, MD, FACS, FAAOBlank
233488 tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
05/15 by John C Hagan III, MD, FACS, FAAOBlank
748543 tn?1463449675
Blank
TMJ/TMJ The Connection Between Teet...
01/15 by Hamidreza Nassery , DMD, FICOI, FAGD, FICCMOBlank
Top Hepatitis Answerers
163305 tn?1333672171
Blank
Rural Mural, CA
1815939 tn?1377995399
Blank
446474 tn?1446351282
Blank
San Francisco, CA
Avatar universal
Blank
317787 tn?1465993311
Blank
DC
1747881 tn?1358189534
Blank
Greeley, CO