Aa
A
A
Close
Avatar universal
hepatitis c and corticosteroids
i have a 55 year old patient with hepatitic c that is only 4 weeks into interon treatment ( on renal replacement therapy i.e HD ) , that has developed decreased hearing in both ears , the ENT specialist soes not think its related to treatment and has adviced a short course of oral steroids . my questions are
1) any link between the hearing loss and interferon in the literature ?
2) how safe is it give him oral steroids at this stage ?
3) is it beneficial to use viral load or liver enzymes as a guide to decide on treatment with steroids ?
Cancel
3 Answers
Page 1 of 1
Avatar universal
It would be wise for your ENT to consult with your hepatologist or doctor who is supervising your hepc treatment and perhaps your Nephrologist to see what your best course of action is.

I've have read where tinnitus (ringing in the ears) has resulted from the the hepc treatment drugs and even a few posts stating they have experienced diminished hearing while on treatment but once treatment ended hearing was restored to normal.  
Steroids are known to suppress the immune system but they're quite remarkable when needed to reduce inflammation and assist in alleviating respiratory problems. I could not advise if a short course of steroids would be safe at this juncture but certainly your hep doc could.

Trinity
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
There are no doctors on here, we're all patients :-) Just so we're clear.

Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
717272 tn?1277594380
There are case studies on the internet about interferon-induced hearing loss.  Patients were usually treated with steroids (immune suppression) after stopping interferon (immune amplification) and hearing was restored.  Some patients continue interferon therapy and the hearing loss clears on it's own but some don't recover.  Do a search with the terms interferon and hearing loss to find those case-studies.

Another approach is to do intratympanic injections with corticosteroids.  The injections allow local application of corticosteroids rather than oral.  You can read more on this topic at http://emedicine.medscape.com/article/857511-print
The treatment is done by an otolaryngologist specialized in procedures and is expensive in the US, about $1500.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Your Answer
Avatar universal
Answer
Do you know how to answer? Tap here to leave your answer...
Answer
Answer
Post Answer
A
A
Explore More In Our Hep C Learning Center
image description
What Is Hepatitis C?
Learn about this treatable virus.
image description
Diagnosing Hepatitis C
Getting tested for this viral infection.
image description
Just Diagnosed? Here’s What’s Next
3 key steps to getting on treatment.
image description
Understanding Hepatitis C Treatment
4 steps to getting on therapy.
image description
Your Guide to Hep C Treatments
What you need to know about Hep C drugs.
image description
Managing Side Effects of Treatment
How the drugs might affect you.
image description
Making Hep C Treatment a Success
These tips may up your chances of a cure.
Recent Activity
667923 tn?1421466324
Blank
skeetelmore65 is hanging in there and thi... Comment
Mar 25
242912 tn?1402547092
Blank
Jade59 commented on  Titrating
Mar 25
317787 tn?1473362051
Blank
Dee1956 commented on meegWpaw's status
Mar 24
Blank
Weight Tracker
Track your weight over time
Start Tracking Now
Top Hepatitis Answerers
317787 tn?1473362051
Blank
DC
163305 tn?1333672171
Blank
Rural Mural, CA
446474 tn?1446351282
Blank
San Francisco, CA
Avatar universal
Blank
1747881 tn?1358189534
Blank
Greeley, CO
2059648 tn?1439770265
Blank
Hepatitis C Community Resources