Hepatitis C Community
high ast and alt on blood test
About This Community:

This forum is for questions about medical issues and research aspects of Hepatitis C such as, questions about being newly diagnosed, questions about current treatments, information and participation in discussions about research studies and clinical trials related to Hepatitis. If you would like to communicate with other people who have been touched by Hepatitis, please visit our new Hepatitis Social/Living with Hepatitis forum

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

high ast and alt on blood test

I recently had a lot of blood work done because I have lupus and a chronic kidney disease.  My results showed the AST(SGOT) was 45H and the ALT(SGPT) was 58H.  Could you please give me some sort of reason for this?  Thank you very much.
Related Discussions
151263_tn?1243377877
I'll give it a stab, although keep in mind I'm not a doctor. Lupus is a term for generalized autoimmune disease, which you probably already know something about. As you've probably already learned, autoimmune disease is where the body's immune system basically becomes confused and starts attacking itself. Autoimmune disorders can involve attacks against various multiple organs/parts including the heart, lungs, joints, kidneys etc. They can also involve the liver, and when that happens it's called Autoimmune Hepatitis, or AIH. AIH can be very subtle in some people, whereas in others it can be very aggressive (and life threatening). AIH varies in intensity from person to person and varies over time for each person. Sometimes it can come and go, sometimes it can flare up dangerously, sometimes it can go away and never come back. If AIH is present, from what I've read its diagnosis is not always easy. But one thing they look for are certain antibodies which are indicative the immune system is attacking the liver. There's several of them including SMA, ANA and a few others that I don't remember offhand (you can google it and learn all about it). Anyway, if these markers are present, and other signs are also present, you may be diagnosed with a form of AIH. And yes another possible indicator of ongoing liver damage is when your AST and ALT are elevated above normal. AST and ALT are liver enzymes that are released from liver cells when they are damaged. So if they're elevated, it's indicative that something is damaging your liver (that "something" might be AIH/lupus in your case).

But try and not get all worked up over this just because your AST and ALT are elevated. They're really not that high at all. My liver enzymes have been higher than yours for, oohhh, about 25 years (from Hep C) and I have minimal liver damage. Many others here are very similar, the liver's a pretty tough cookie. Plus it can regenerate and heal itself if you resolve the AIH or whatever it is that's eating at it.

Lastly, AIH can and usually is treated successfully. As far as I know most people live out full lives with it. Treatment involves prednisone and/or imuran, which I suspect you already know about having lupus. Hope some of this helps, best of luck to you.
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Hepatitis C Community Resources
RSS Expert Activity
233488_tn?1310696703
Blank
New Cannabis Article from NORTH Mag...
Jul 20 by John C Hagan III, MD, FACS, FAAOBlank
242532_tn?1269553979
Blank
3 Reasons Why You are Still Binge E...
Jul 14 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Emotional Eating: What Your Closet ...
Jul 09 by Roger Gould, M.D.Blank
Top Hepatitis Answerers
Avatar_f_tn
Blank
dontworry_behappy1
163305_tn?1333672171
Blank
orphanedhawk
Rural Mural, CA
Avatar_f_tn
Blank
nan535
Brooklyn, NY
446474_tn?1404424777
Blank
HectorSF
CA
1815939_tn?1377995399
Blank
pooh55811
96938_tn?1189803458
Blank
FlGuy
South, FL