is there chance of liver cancer with high sgpt levels?

is there chance of liver cancer with high sgpt levels?

[HectorSF]

What is causing the high sgpt (ALT) level.
How high is the level?

ALT has no correlation with the incidence of liver cancer.
The only blood maker related to liver cancer is AFP.

Moderate levels of AFP (even almost up to 500 ng/ml) can be seen in patients with chronic hepatitis. The sensitivity of AFP for liver cancer is about 60%. In other words, an elevated AFP blood test is seen in about 60% of liver cancer patients. That leaves 40% of patients with liver cancer who have normal AFP levels. Therefore, a normal AFP does not exclude liver cancer. Any patient with cirrhosis and an elevated AFP, particularly with steadily rising blood levels, will either most likely develop liver cancer or actually already have an undiscovered liver cancer.

The majority of hepatitis C virus patients with liver cancer have cirrhosis. In several retrospective-prospective studies (looking backward and forward in time) of the natural history of hepatitis C, the average time to develop liver cancer after exposure to hepatitis C virus was about 28 years. The liver cancer occurred about eight to 10 years after the development of cirrhosis in these patients with hepatitis C. Several prospective European studies report that the annual incidence (occurrence over time) of liver cancer in cirrhotic hepatitis C virus patients ranges from 1.4%-2.5% per year.

In hepatitis C virus patients, the risk factors for developing liver cancer include the presence of cirrhosis, older age, male gender, elevated baseline alpha-fetoprotein level (a blood tumor marker), alcohol use, and co-infection with hepatitis B virus.

Cheers!
Hectorsf