The protease inhibitors cause resistant variants of the original (called "wild type") virus to form. The hope is to knock out the wild type virus quickly, before this happens. If you do relapse, and resistant variants have formed, you can't use the available PIs again to treat because it won't work -- your virus has now mutated to be resistant to those drugs.
I do think they are trying to find new PIs with different resistance profiles (i.e. they cause different types of resistant strains to form). If this succeeded, I think it would theoretically be possible to re-treat with a different PI that had a different resistance profile from the one you originally took.
Copyright 1994-2016MedHelp International.All rights reserved. MedHelp is a division of Aptus Health.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.