Aa
A
A
Close
Avatar universal
is this true
If you relapse on PI can you treat with them again at a later date. Roscoe just read from a pamlet and its says you can't if i understand it correctly? can anyone elaborate, thanks Diane
Cancel
1 Answers
Page 1 of 1
971268 tn?1253204399
The protease inhibitors cause resistant variants of the original (called "wild type") virus to form.  The hope is to knock out the wild type virus quickly, before this happens.  If you do relapse, and resistant variants have formed, you can't use the available PIs again to treat because it won't work -- your virus has now mutated to be resistant to those drugs.

I do think they are trying to find new PIs with different resistance profiles (i.e. they cause different types of resistant strains to form).  If this succeeded, I think it would theoretically be possible to re-treat with a different PI that had a different resistance profile from the one you originally took.  

Someone please correct me if I'm wrong.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Your Answer
Avatar universal
Answer
Do you know how to answer? Tap here to leave your answer...
Answer
Answer
Post Answer
A
A
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
What Is Hepatitis C?
Learn about this treatable virus.
image description
Diagnosing Hepatitis C
Getting tested for this viral infection.
image description
Just Diagnosed? Here’s What’s Next
3 key steps to getting on treatment.
image description
Understanding Hepatitis C Treatment
4 steps to getting on therapy.
image description
Your Guide to Hep C Treatments
What you need to know about Hep C drugs.
image description
Managing Side Effects of Treatment
How the drugs might affect you.
image description
Making Hep C Treatment a Success
These tips may up your chances of a cure.
Recent Activity
317787 tn?1473362051
Blank
Dee1956 Praying for those affected ... Comment
Oct 15
317787 tn?1473362051
Blank
Dee1956 commented on KeeLolo's status
Oct 15
Avatar universal
Blank
iLiz commented on Quad pain right leg
Oct 14
Blank
Weight Tracker
Track your weight over time
Start Tracking Now
Top Hepatitis Answerers
Avatar universal
Blank
317787 tn?1473362051
Blank
DC
1747881 tn?1358189534
Blank
Greeley, CO
683231 tn?1467326617
Blank
Auburn, WA
7469840 tn?1409849436
Blank
San Diego, CA
Avatar universal
Blank
Hepatitis C Community Resources