Aa
medicine
WHAT IF THE PEGASYS IS LEFT OUT OF REFRIGRATOR WHAT IS THE DEMAGE DONE TO THE MEDICINE?
The best thing to do is phone your Pegasys provider and discuss your situation with the pharmacist, preferably a Roche specialist.
Different interferons may have different storage requirements.
Interestingly, my own Roche-associated pharmacist was more concerned about freezing than leaving meds at room temperature. (He warned me to never freeze the peginterferon, even for a second.)
Apparently, Roche studies have shown Pegasys can survive up to six days without refrigeration to about 12 C but doesn't survive freezing at all.
Roche tested it as safe up to 24C but recommends a limit of 12C. (The ribavirin isn't sensitive to temperature in the same way.)
He also said, by the way, that it's very important to not shake the Pegasys.
This was after my fridge broke down and I was very concerned (freaking out) that my Peg hadn't been at ideal temperature.
Even though according to him it was okay, he sent me replacement interferon anyway, for my peace of mind. (I returned the ones in question.)
That was super. I didn't want to take the slightest chance, no matter what, since I was over-the top anxious about messing up treatment.
Give your pharmacist a shout and see what he says.
Best wishes,
Susan
.
Different interferons may have different storage requirements.
Interestingly, my own Roche-associated pharmacist was more concerned about freezing than leaving meds at room temperature. (He warned me to never freeze the peginterferon, even for a second.)
Apparently, Roche studies have shown Pegasys can survive up to six days without refrigeration to about 12 C but doesn't survive freezing at all.
Roche tested it as safe up to 24C but recommends a limit of 12C. (The ribavirin isn't sensitive to temperature in the same way.)
He also said, by the way, that it's very important to not shake the Pegasys.
This was after my fridge broke down and I was very concerned (freaking out) that my Peg hadn't been at ideal temperature.
Even though according to him it was okay, he sent me replacement interferon anyway, for my peace of mind. (I returned the ones in question.)
That was super. I didn't want to take the slightest chance, no matter what, since I was over-the top anxious about messing up treatment.
Give your pharmacist a shout and see what he says.
Best wishes,
Susan
.
Keeping prefilled syringes at temperatures outside the recommended range of 36 degreeF to 46 degreeF can destroy the medicine. Do not use the medicine if it is cloudy or has particles floating in it.
Trinity
Trinity
If the premixed interferon has been allowed to warm to room temperature for an extended period, you should probably call the manufacturer and request a replacement. Roche Pharmaceuticals maintains a toll free hot line; give them a call and discuss your situation with them.
I believe proteins in the medication can ‘denature’, possibly affecting treatment outcome.
--Bill
I believe proteins in the medication can ‘denature’, possibly affecting treatment outcome.
--Bill
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