Hepatitis C Community
neutropenia !!!
About This Community:

This forum is for questions about medical issues and research aspects of Hepatitis C such as, questions about being newly diagnosed, questions about current treatments, information and participation in discussions about research studies and clinical trials related to Hepatitis. If you would like to communicate with other people who have been touched by Hepatitis, please visit our new Hepatitis Social/Living with Hepatitis forum

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

neutropenia !!!


guys i just got my reports from a CBC done 4 weeks ago...

i have neutropenia for the first time... and didnt even know it.

WBC 3.1

neutrophils 28%

that means ANC is 0.28 x 3100 = 868.

now does that warrant a neupogen shot?  whajt do u think guys?


i have only 2 shots of pegasys left to do...


Related Discussions
5 Comments Post a Comment
Blank
Avatar_m_tn
Just a few shots to go! Congratulations!.

Your ANC is fine according to most treatment guidelines. Every treating doctor has different thoughts on this, but mine is hesitant to give Neupogen unless the ANC goes down as low as 300. Mine is currently 500. I don't think they have really linked increased infections to lower ANC's.

Especially since you're almost done with treatment, if it were me I'd just leave well enough alone.

Best luck!!

Mark
Blank
151263_tn?1243377877
I'm in the Vertex study and they use a neutrophil threshold of 750 for IFN dose reduction (or the use of neupogen). But like mark says I've heard experienced hepatologists will commonly allow neutrophil values well below 750, I've even heard as low as 300 is ok if you are otherwise in good health. Also, from my experience neutrophils can go up and down during treatment. Mine were 500 on my last blood work, and they'll probably go back up to closer to a 1000 next time. So don't be surprised if your next value is higher than this one. Unless they're is something "special" or out of the ordinary that would make your low neutrophils a more significant problem than your average/otherwise healthy HCV patient, then I wouldn't worry at all about 850 neuts. Just wash your hands alot and try and stay away from sick people. Also put antibiotic/antiseptic creams on cuts and keep them covered/clean at all times (i.e. you're more prone to infections when your neuts are low).

Otherwise, being so close to the end of treatment, I'd say you're going to make it just fine. Hang in there and here's to your SVR - best of luck.
Blank
Avatar_m_tn
Do not worry, ANC of 500 is cause for concern and rescue med.  Also, rescue med is very effective AND *FAST* acting.

I hovered betwixt 700 and 1100 throughout tx and only medicated when I dipped below 600 and 500 on a few occassions.  On all occasions I did a shot a day for three consecutive days and CBC on 4th or 5th day after first shot.  In all cases, I was normal, high normal, or slightly above normal in my ANC measurement with it dropping back to the tx range I previously mentioned.

It seems to me that you've come along way from where you were when you started tx and this is just another of those factors which do occur and it's good to be aware of them.  This finish line is in sight and I would think that you should be able to cross it without this being any obstacle in doing so.  Wish you well with remaining tx.
Blank
Avatar_n_tn
No. I think you will get by without any Neupogen. Congratulations
Blank
Avatar_m_tn
No. No. No.

My abs neuts went as low as 320 and my doc still didn't feel I needed Neupogen. "868" is out of the Neupogen range by almost all standards. You only got two weeks left. Not to worry.

Be well,

-- Jim
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Hepatitis C Community Resources
RSS Expert Activity
242532_tn?1269553979
Blank
The 3 Essentials to Ending Emotiona...
Sep 18 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Control Emotional Eating with this ...
Sep 04 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Emotional Eating Control: How to St...
Aug 28 by Roger Gould, M.D.Blank
Top Hepatitis Answerers
1815939_tn?1377995399
Blank
pooh55811
Avatar_f_tn
Blank
nan535
Brooklyn, NY
446474_tn?1404424777
Blank
HectorSF
CA
Avatar_f_tn
Blank
Livelife777
683231_tn?1408489117
Blank
flyinlynn
Auburn, WA
Avatar_f_tn
Blank
dontworry_behappy1