non responder

Can you going through treatment again after being a nonresponder & is treatment successful second time around.
I went from 2,000,000 viral load to 25,000 in a three week period. After 6 months I was at 5,000 and the doctor took me off the meds. I protested along with the nurses but it did not matter. My biopsy was stage 1 after 38 years with the virus.
I,m hesitant to go through the treatment again with the same results.
Danny

[Rockerforlife]

Sorry,but as i understand this,you are a "nul-responder"...this means you have never went UN on this type of tx...studies prove your odds are very low to clear with PEG and RIBA,which is what i persume you were on...looks like you need the Teleprevir or Boceeprevir drugs in combo with the SOC drugs....this is my take on this...BTW..im a slow responder ...i cleared at week 12...if you dont clear by wk 24...another option is too to daily meds  called interfergen...which is a tough tx..you are very lucky to bs a stage 1....good news...get in on one of thr trials...they are available


r.s

[zazza]

If you dropped 2 logs by week 12, i e down to 20'000 IU/ml, you would be a partial responder since you were not UND by week 24.

I figure you got a good chance of clearing if you add a protease or polymerase inhibitor to SOC, since you obviously respond to interferon albeit not enough. Getting into a trial might be a good idea, as long as you are certain you are getting the new drug as well and not just standard treatment.

With such a good biopsy result you can also wait until the new drugs are approved. Hopefully that will not be too long, perhaps 2011.