pomegranate and Tx ????

I have heared from an ex-patient (SVR) that his doctor advised him to take pomegranate juice during Tx as  pomegranate/pomegranate juice is very very helpful during Tx and is very bebnificial to liver. Anyone know about that ???? please share if you any info

[meakea]

I don't know about doctor recommendations but I drink a little pomegranate juice every morning.  I've been on TX for 5 weeks and I was undie at week 4.  I am not saying the pom juice had anything to do with those results though.

[FlGuy]

Maybe the doc was invested in pomegranate futures.

[scruples]

Thats really funny but as per my info there are commodity Futures/Forwards available in our part of world :) May be he himself like pom juice.

Anyhow apart from juke, is there no scientifically proven research about pom juice effects during TX????

[CoWriter]

Pomegranate juice inhibits CYP3A activity...same as grapefruit juice.  That means that if you happen to be taking any medications that are metabolized by CYP3A, (like some blood pressure medications) the pomegranate juice can cause the levels of those medications to be increased, which can be dangerous.



"Inhibitory effect of fruit juices on CYP3A activity."

http://dmd.aspetjournals.org/cgi/content/abstract/34/4/521?ijkey=8fc3bc688dccea368d29077e08e6a92230856feb&keytype2=tf_ipsecsha

[merryBe]

yeah I agree here, lots of juices are heathy under normal circumstances, but can mess with drugs and with iron loads etc. effects on cyp3A And P450 are being examined a lot these days.

mb