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This is round 2 of treatment for me--finished 48 months in June 2011-peg and ribo only, had a relapse by 3 month checkup.  I started triple therapy, peg, ribo and incivek on Feb 27, 2012.  I feel wiped out compared to the last treatment-I started with rectal bleeding this past week along with horrible heartburn and difficulty swallowing.  I gets very painful to drink anything, solids go down ok-weird!  I haven't heard anyone else complain of the reflux type symptoms-----Please respond if you have had this issue.
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4950316 tn?1394184585
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Good luck.
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Avatar universal
I am also having exactly what you are having.......  I have gotten a metal taste in my mouth  and the heartburn.... I am already on acid reflux med and its not working at all......  my nurse said to drink choc milk with the pills and well it does really work more than 5 mins...... this phlegm is driving me crazy as well
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Avatar universal
thanks, I appreciate the input--take care
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766573 tn?1365166466
Two weeks into Incivek I developed acid reflux. The first time I had heart burn I did not know what it was. I chewed baby aspirin at first since it felt like a heart attack. Then I ate Tums like crazy, which does zero for medication-related GERD.

Anyway, I had difficulty swallowing, my throat felt thick and even hours after I ate I would have acid reflux burbs. I would get a horrible taste in my mouth at night and in the morning my breath  was so gross. Gah!

I just read about it here on the Forum and began taking a Zegerid (omeprazole/sodium bicarbonate) in the mornings. I did that for a couple of weeks and the problem just kind of resolved itself. I guess it had a lot to do with the kinds of fats I was eating, my routine and a few other things - in addition to the Incivek, of course.

Hope you feel better♫
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Avatar universal
thanks, and I believe it's from the Incivek too.  6 more weeks of this and hopefully it will go away.  take care.
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Avatar universal
I agree, did you do triple therapy the first time.  I think its the Incivek that is doing this.  Thank you and good luck to you as well.
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Avatar universal
thank you I will.  I hope you feel better too,  Good luck
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1815939 tn?1377991799
Hopefuly your doctor can find the cause and give you some prescriptions for it.

I just wanted to add that my reflux problems, the burning in the esophagus, the belching and the gas all resolved almost immedicatly after I finished Incivek. Hopefully yours will too.
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Avatar universal
  One more thing I did Treatment before and it was not as bad. This time It just wiped me out.It is rough but you can do it. Keep your Dr posted on any and all side effect.  Good luck
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Avatar universal
I had acid reflux before starting treatment.  Somedays on treatment I felt like flames were coming up my throat. I was told to take prilosec frist thing in am before you eat anything Even with prilosec it still burned. When you have to eat all that fat morning noon and night. I know that zofran more for nausea but it did help the acid.
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1995824 tn?1330379049
Just to add quickly to the other replies, I had the same problem with major indigestion, gas, burping...you name it. It took a combination of anti-nausea medicine and also taking Prilosec OTC at bedtime to break the cycle. But I also agree with hector....abdominal pain is not a good sign. You do need to address that with your doctor as soon as possible.
Feel better.
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Avatar universal
thank you, I appreciate it. good advice
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Avatar universal
thanks, I appreciate it..I will call my doc tomorrow
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Avatar universal
WOW, hope you feel better and thanks,  I also have noticed alot of dryness in my nose
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446474 tn?1446347682
You should not have continuous abdominal pain ever. Go see your gastroenterologist you may have Gastroesophageal reflux disease (GERD). This is when the acids from your stomach "flow back" into your esophagus, causing discomfort and pain. It can also cause dysphagia (difficulty swallowing), hoarseness and regurgitation.

All very unpleasant but usually easily treated. Their are a number of types of medications that work for different patients. GERD is not something you can treat yourself with antacids. Antacid are NO recommended for people with GERD. GERD needsd to be treated as It can cause the stomach acids to damage your esophagus. Not something you want to have happen.

Your gastro should be very familiar with treating GERD.

I am currently having some GERD myself and it is no fun.

Good luck.

Hector
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1815939 tn?1377991799
I was on Incivek from Sept. 26th to Dec. 18th. I had a lot of gastrointestinal symptoms.

I was always bloated and nauseated until I got on Zofran. I had heartburn and gastric reflux, especially at night. I was always belching (and passing gas). I took some calcium carbonate chewable tabs for the heartburn but not too close to the Incivek. I also had some anal/rectal issues. I think those are all normal for those of us on Incivek. I was also very fatigued but I felt much better once I was off Incivek.

Your symptoms seem more severe, though. I think you should call your doctor about the rectal bleeding. It could be hemorrhoids, possibly internal hemorrhoids, or it could be something more serious. Your heartburn sounds pretty bad. If it is difficult to swallow and painful to swallow liquids that also sounds like it needs attention. If I were you I would call my doc in the am and see if you can get seen. Even if you do not have some serious problem causing your symptoms, hopefully the doc can order you some prescriptions to ease your discomfort and stop the heartburn. They also need to figure out where that rectal bleeding is coming from.

Hope you feel better soon.

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Avatar universal
Yes, I have seen this question posted before here, and the person called his Doctor right away, and was prescribed an effective acid-reflux med for that, so check with your Doctor ASAP.
   I'm on the other PI, Victrelis, it had s 4 week leadin, withg just the Inf/Riba, and all was fine. As soon as I starteed the 3rd med, literally, 10 minutes after I popped the for pills, I had a bitter taste in my mouth, and horrible heartburn.
   I have a painfully sore-throat, and just noticed blood, when I spit out some phlegm, which didn't surprise me, because my throat is painfully raw, and the inside of my nose is dry, and when I blow it, I often see blood.
   Triple tx has more sides, unfortunately. The Incivek has the anal problems, but I also felt "the burn" from the Victrelis, when I began. I went and ordered this little "Mr Shower" nozzle, that fits on my bath-tub faucet, and wash after I go to the bathroom, which helps alot. And I changed my diet drastically: no more spicey foods for me, no more garlic, no more onions. I basically eat like a baby now: yogurt, bananas, apple-sauce, rice.
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