sofosbuvir - trials

[cassiopea]

hi everyone, i'm Cassy from. italy, i'm 38 and hcv 1a since 22 years; i've never tried to cure this because of a allergy to interferon;at the moment in italy there are only 2 hospitals where you can ask for interferon- free but it's very hard to enter it..how is the situation in yours country?? thank you and forgive my awful english. Cassy

[cassiopea]

the doctor has just sent me un e-mail: i'm still undetectable !!!6 months after E.O.T!!! I'M SO HAPPY!!!! this treatment really works! don't give up the fight!! keep on fighting guys because a new dawn is coming for all of us !!kisses cassy

[cheflady]

Well what a way to start the new year in Well done you and i wouldnt worry that you had a few beers my hubby drank a good few times throughout tx and he still SVR, just concentrate enjoying your new hepc life. Well done again Cassy love Jules x

[Dee1956]

Cassy!  So glad to see you.  Don't worry. As my son would say, that bell has been rung.  You did it, it is over and now on to SVR

I am very happy for you.
Dee

[cassiopea]

hi ! today is my last day of trial and i make my blood work; since the E.O.T. ( 26/7/13) i'm still undetec. and i hope it will remains the same this time! i'm a bit worried because i drank some beer on the new year's eve...my doctor said it's okay if i drink two o three times a month..but i'm still worried..maybe i made a huge mistake..kisses Cassy

[cheflady]

hi there congratulations you must be thrilled fingers crossed for those three little letters SVR !! Well done Jules

[cassiopea]

hi everyone! i'm very glad to inform you that after 12 weeks after the end of treatment i'm still undetectable!!there's no virus in my blood!!!!! next january there'll be the next bool work ( after 24 weeks ) but the doctor told me that to be undetecable right now means i colud probably mantein this forever.. that treatment is really working!!
p.s. to ramesh123; in italy doctors say that the wind period is about 6 months but 5 months can be enough time so i think you could relax!
bye bye
Cassy

[ramesh213]

hai sir i had hiv rapid test after 4and half month with immunocromatograpic rapid test it is nagative,and also i had hbsag and hcv antibody test after 5 monthes both are nagative are these results are conclusive or should i go for any other tests what was the wind ow period for hiv and hapatities b and c,if coinfected window period will change in this case ......please help me in this case thank you.

[mzkity]

I'm so happy for you. Just seems like yesterday that you started!! :)

Kitty

[BoceprevirGal]

    Hi Cass, and thanks for keeping us posted. Congrats on finishing your Treatment!  My husband has 1 more week to go, on his 12 week Trial with some AbtVie Trial meds (phase 3, with the riba, plus the Abbot meds used in The Aviator Study)
   He also was Undetected at week 4, and it's hard for us "old-timers" to believe in a 12 week Tx, but yes, believe, these Trials are yielding excellent results!

[cassiopea]

thank you! i hope this treatment will work even if 3 months is a very short period of time to destroy the enemy!!! grazie mille!!!

[rivll]

Wow, that was a quick treatment. I am happy you are feeling well and hoping you achieve SVR.
Please keep us informed.

I miei migliori auguri per il futuro :-)

[cassiopea]

hi everyone! i've just finished my treatment and i feel fine! after one week i feel better and stronger than ever!! the first exam is scheduled for august the 26th..i'm a bit nervous but i'm trying to calm down...i did every thing i could to heal this disease..and now all i have to do is wait and see! kisses Cassy

[mzkity]

So glad to here your good news!!! I read in the other post your job is so far away, but you are so determined. Very happy for you!!! :)

[rivll]

Hi Cassy,
I am very happy that you have kept us informed and that you are doing so well.
Excellent news. Please stay in touch.

[cassiopea]

thank you very much for your advice! by the way, i feel fine, only a bit  tired but the doctor said it's normal! today a friend of mine, who is in this trial too ( but she's in the arm without ribavirin) told me that her hcv viral load is undetecable! maybe we colud get rid of ribavirin in the next future? i hope so..i feel we are going to achieve our goal! to find a short and well- tolerated treatment for all of us!kisses

[Dee1956]

Hi here is an ongoing conversation about the trial, I think this is the one you are on.  It is very interesting, I thought it might be helpful

http://www.medhelp.org/posts/Hepatitis-C/Starting-Sofosbuvir-GS-5885/show/1875802

[Dee1956]

Hello there, this is wonderful news!  I am so very very happy for you!

How are you feeling?  If you want to see some other people on this trial you can go to the top of the page, click on the magnifying glass, type in your soofosbuvir and you will find others talking about it.
If you can find, let me know I will find and send some addresses to you.

Your English is perfect by the way :)

Again, so excited for you, no interferon WOO HOO!!

[cassiopea]

i have some news....after only 2 weeks of treatment......UNDETECTABLE!!!  am i dreaming????i couldn't believe it..but when i saw this word by myself today..i only thought: thank God!!!!!!!! i know it's to early to be happy, i know i have to wait after finishing the treatment and more but i really hope it will work..the doctor told me that i'm one of the lucky patiences who is not detect. after 2 weeks..in general it takes 4 weeks to be so...guys...my heart is full of hope not only for myself bur for everyone who has been waiting for a solution to this damned deasese...maybe something's changing and it' s getting better for everyone! bye CAssy

[cassiopea]

hi everyone!
the first 18 days are gone! i feel good, the side effects aren't so bad..just insomnia and fatigue but not too much, i can go to work every day and i keep on doing some sport whenever i can..the next blood test is skeduled for the end of the month and then i will discover if i'm undetectable. i will inform you as soon as i can! bye bye Cassy

[cassiopea]

i think the chances of SVR could be higher with a treatment 48 weeks long; my doctor told me that you can achieve SVR after 48 weeks ,60 -70 % of his patients witk genotype 2 and 3 achieved SVR after that period of time, so don't be sad you can get it!

[chirag0019]

thanks for a best advise and grow up my mind strenth...
how many percent of chances to take a dose of 48 weeks with int + rbr  ?

[cassiopea]

i'm really sorry for what happened to you..i could imagine how you feel about it! but you're not old you can try again! if you ask me if it would be better to wait for new treatment with sofosbuvir i think it coulb be at your own risk: i mean, i don't know when this new drug could be avaible for all patients..here in Italy also boceprevir and telaprevir are not avaible yet for all patients so i think it takes a lot of time until everyone could use sofosbuvir..my advice is not to wait and try again with pegasis and ribavirin, i know a lot of people (genotype 3) who have been not detect after 48 weeks of treatment!! be strong, re-gain your energy and start another battle against the enemy!

[chirag0019]

NAME: PURIBEN K PATEL                  AGE/SEX:   60/FEMALE

 12th APRIL 2012 Test is done HCV (+VE)

 30TH APRIL 2012 1)   HCV VIRAL LOAD *42500
                 2)*GENOTYPE 3

 15TH MAY 2012:        TREATMENT PROTOCOL STARTED
Inj. Pegasys 180 mcg 1 per every week for 24 weeks
        Cap. Ribavarin 200 mg 2-0-3 for 24 weeks

• After 4th week of treatment 12th JUNE 2012 – VIRAL LOAD *52

• After 12th week of treatment 26Th AUG 2012 – VIRAL LOAD *BELOW 15

• After 24th week of treatment 29Th OCT 2012 – VIRAL LOAD *BELOW 15

• After 24th week of treatment 29Th OCT 2012 – **NOT DETECTED


 26TH APRIL 2013 (after 6 month of treatment) AGAIN TEST IS DONE

RESULT: - VIRAL LOAD *1,06,000

I have two doctors suggestion.
---->One doctor told repeat this Treatment again 48 weeks.But my mother is not acceptable for this treatment.
---->Second doctor was told---> not better result in this treatments and not acceptable this dose of patient of
                                              this age.If you are collect medicine SOFOSBUVIR and treat this petient than
                                               we hope better result.
Dear all,
Please help of this Case.

[xann]

Thank you very much for your answer. I would like to find a trial in Germany (where i live) for my father, who lives out of hier, not in EU. But he could surely stay by me during the trial, it's not a Problem. I just don't know if only the residents of the country could participate. May be there are some rools, that says that in the Trials in Italy only the Italien residents can participate. Thats what i mean.
You are absolutly right, you have won a lottery! I really really glad for you, because i really know how much it means. You have got a great Chance.