starting triple tx

my meds are being delivered sometime tomorrow, should I wait till the following morning to start tx would be starting with incevik at 7:00, then riba at 8:00, then my shot at 9:00, then 2:00 incevik then 7:00 incevik and finishing with riba at 8:00. Does this sound like a plan I treated a year ago and that was my shedule8:00 riba, 9:00 shot and 8:00 finishing with riba, any sugestions appreciated thanks Stalion

[pooh55811]

I think they say to take Incivek within 30 minutes after eating the meal with 20 grams of fat so that people do not get confused and take it 30 minutes before eating. Technically you could take it right after you eat or within the 30 minutes after you eat.

Here are a couple of links:

How should I take INCIVEK?

http://www.vrtx.com/current-projects/approved-medicines/incivek.html

"Take INCIVEK exactly as your healthcare provider tells you. Take two INCIVEK pills 3 times a day, 7 to 9 hours apart, with food. Eat a meal or snack containing about 20 grams of fat within 30 minutes before you take each dose."

http://www.drugs.com/incivek.html

"The usual dose of Incivek is 2 tablets taken 3 times per day, every 7 to 9 hours. Follow your doctor's instructions.

Take Incivek within 30 minutes after eating a meal or snack that contains about 20 grams of fat. Always take Incivek with food. Examples of snacks that contain about 20 grams of fat include: A bagel and cream cheese, 3 tablespoons of peanut butter, 2 ounces of American or cheddar cheese, 2 ounces of potato chips, a half-cup of nuts or trail mix, or 1 cup of ice cream."

I hope you keep us posted on how things are going. Best of luck.

[hrsepwrguy]

You need to take your incivek 7 to 9 hrs apart (every 8 hrs) very important.
6-2-10 or 7-3-11 but stay in the 7-9 hr window even over night

Good luck getting started

[crigger]

Be sure to eat your 20 grams of fat Too. Good luck with treament! You are in for a roller coster ride. The people on this forum have been great.  Some people here really know all about the disease and treatment,

[pooh55811]

As can-do said, the Incivek needs to be taken every 8 hours. It has a short half life and if you allow too much time in between doses, you have a greater chance of developing mutant resistant strains of Hep C (and potential treatment failure).

When I started treatment I started the first day in the morning at 6 am with the Incivek and the Riba. Then 2 pm Incivek, 6 pm Riba, and 10 pm Incivek. I took my injection at 8 pm that first night.) As crigger mentioned, you need to eat 20 grams of fat about 20 minutes before taking the Incivek (every time) and you need to take the Riba with "a substantial meal." I always ate something solid with all of my doings in addition to the 20 grams of fat. I took the am Incivek with the Riba but I know some slpit them up. Riba should be about every 12 hours.

The scheduling can be a challenge because for each dose you have to get up, fix food with 20 grams of fat, eat, take the pills. So you get up before 6 am (maybe 5:30 am) for the day's first meal, then take your pills. Then you repeat all of that each time you take a pill, with your last doese being about 10 pm.

With the Incivek (and the Riba), you will most likely need to set alarms or you will forget and miss doses.

Congratulations on starting treatment. Many of us have been through treatment with Incivek so we have a pretty good handle on possible side effects and how to treat them. If you get any side effects come onto the forum and ask questions. We will help. Stay on top of any sode effects you get. They will snowball if you do not.

[stalion]

I meant to say I was going to take the incevik 7 ,2 ,10,then the riba 8 and 8pm .The material I got said to take 20 grams of fat at the time of the meds you are saying to  eat 20 grams 20 minutes before. I am planning on eating peanut butter it is fast and easy, plus I had a bad spinnal injury, and also take thyroid meds, plus tramadol, so this is going to be a little tricky, I usually take my thyroid med at 4am and plan on taking tramadol at 6 am, I do not want to taxt my liver any more than I have to. Thanks for the advice

[pooh55811]

I think they say to take Incivek within 30 minutes after eating the meal with 20 grams of fat so that people do not get confused and take it 30 minutes before eating. Technically you could take it right after you eat or within the 30 minutes after you eat.

Here are a couple of links:

How should I take INCIVEK?

http://www.vrtx.com/current-projects/approved-medicines/incivek.html

"Take INCIVEK exactly as your healthcare provider tells you. Take two INCIVEK pills 3 times a day, 7 to 9 hours apart, with food. Eat a meal or snack containing about 20 grams of fat within 30 minutes before you take each dose."

http://www.drugs.com/incivek.html

"The usual dose of Incivek is 2 tablets taken 3 times per day, every 7 to 9 hours. Follow your doctor's instructions.

Take Incivek within 30 minutes after eating a meal or snack that contains about 20 grams of fat. Always take Incivek with food. Examples of snacks that contain about 20 grams of fat include: A bagel and cream cheese, 3 tablespoons of peanut butter, 2 ounces of American or cheddar cheese, 2 ounces of potato chips, a half-cup of nuts or trail mix, or 1 cup of ice cream."

I hope you keep us posted on how things are going. Best of luck.

[Advocate1955]

My husband started everything on a Friday, so that he would always have Sat-Sun to rest up a bit from the injection.  He works swing shift, so he created his schedule around leaving for work at 2:30 PM and getting home about 11:45 PM.  His schedule while on Incivek was:
7:30 AM:  fat snack
8:00 AM: Incivek
10 AM:  Ribavirin
2 PM on Fridays:  Interferon
3:30 PM:  fat snack
4 PM:  Incivek
8 PM:  Ribavirin
11:45 PM:  fat snack
12:15 AM:  Incivek
As others have said, 8 hours between doses of Incivek, and 10 hours between doses of Ribavirin.
For my husband, doing the injection before leaving for work on Friday afternoon meant not having more difficult side effects until later in the evening and on Saturday, while at home from work.  Also, starting everything on the first Friday of treatment meant the end of each week being the end of a full 7 days of everything.
After he finished the Incivek, he modified the schedule a little bit so he wouldn't have to wake up so early, given that he works late.
Hope this helps.
Advocate1955

[stalion]

                                                                                                                                want to thank you all for your good advice, like I said I would not had made it through the last tx with out the help of people on this forum thanks again Stalion

[ceanothus]

You mentioned a spinal injury, and I wondered whether you require narcotic pain meds for that? I'm in that situation myself and I discovered that the Incivek interacted with my pain meds to amplify them. It was slightly scary the first day until I realized what was going on and cut the dosage of the pain meds. I went from 4 pills/day to 2 pills/day. None of my doctors had mentioned that possibility!

[stalion]

no I take tramadol, and 800 ibuprofen, it does not really help but it is better than nothing , I am going to try some pain management when I am done with tx.

[FrontRangeMom]

My doc said don't take ibuprofen during treatment, use acetaminophen but not more than 2000 mg total per day (I was on triple with incivek but have finished that, now on RIBA + IFN).

Make sure you spread those incivek doses out, 7-9 hours apart. It always surprises me that people are handed these powerful drugs without being given all the instructions on how to use them,

[LookingForward12]

Yep. Ditto on the Incivek being  as close to exactly 8 hours. I was religious about it the first four weeks....and still pretty much am, although I don't freak out if it is 30 minutes late or early now. I am still I. The 7-9 window. I kept a spreadsheet of my dose times and what I ate each time. Helped me to stay on schedule.  I could send you a copy if you want.
The other thing with me, is that since you have to take the ribavarin with food too, you may want to take your first dose with your morning Incivek and your afternoon dose around 5-6 with another light (near regular dinner time) but normal meal. I had terrible Insomia that was exacerbated by the ribavarin and found that 5pm helped with that. I also ended up taking 600mg in the morning and 400 mg in the evening. I don't do well with any kind of drug that speeds me up.
Congratulations on beginning treatment. Inagreenthatnyou may want to start on Thursday or Friday so that you have the weekends for just laying around and taking care of yourself.

[stalion]

                                                                                                                                    Thank you all for your support and concern!

[80mecheng]

I have never seen any recommendations to separate Riba from Incivick just to take it with food.  I am on Vic but researched both prior to starting.  Bottom line is 7-9 hr duration between Incivick (6AM, 2PM, 10PM), Riba with breakfast/dinner, shot same time (about) every week.  I take Riba/Vic at the same time in the morning after I eat something.  The schedule you listed is not consistent with typical recommendations.  You should confirm with your doctor since most of us are novices.