Aa
A
A
Close
Blank
1084115 tn?1385232189
svr rates with reduced riba
hello,

i read somewhere in this forum that reduced riba after 12 weeks does not have an impact on svr rates.
but i cant no more find this posts/topic.
iam still on 800 mg(copegus) (iam 50 kg)till my hgb is stable, and my doc maybe wants me to keep on this dose.
normally i had 1000 mg.
i was UND week 4+12 and wonder if this 200 mg less will have an effect on my svr chances.

thanks for some infos or links to this topic
Cancel
6 Answers
6 Answers
Page 1 of 1
Avatar universal
As long as you are taking the Riba, the dose reduction won't matter.
Comment
Cancel
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
Guy your going to stress yourself to death.... Good luck.

In clinical trials, anemia was managed with RBV dose adjustment only; use of erythropoietin was not allowed in the studies of telaprevir. The SVR rates remained high in patients undergoing RBV dose reductions for anemia in ILLUMINATE and ADVANCE[21]; indeed, SVR rates were 76% for patients who underwent RBV dose reductions and 72% for patients who did not reduce their dose of RBV. Therefore, these data strongly indicate that the management strategy for anemia should be to first reduce RBV. Although erythropoietin was not used in the registration trials, there may also be a role for its use in patients who develop symptomatic anemia during telaprevir-based therapy, primarily to avoid treatment discontinuation or interruption due to anemia.  

http://www.clinicaloptions.com/Hepatitis/Annual%20Updates/2011%20Annual%20Update/Modules/DAA%20Naive/Pages/Page%206.aspx
Comment
Cancel
Avatar universal
Comment
Comment
Submit Comment
1084115 tn?1385232189
thanks for the infos.

@can-do-man,
iam working on my anxiety with my doc and its getting better,slowly.
thanks a lot

Comment
Cancel
1084115 tn?1385232189
Comment
Comment
Submit Comment
2004810 tn?1365157211
Hi,
that was good news to me too, after reading can-do-man's answer cause I'm waiting for my 12 weeks results to hopefully reduce on the Riba (if still UND). I'm on 800 mg now but will hopefully reduce to 600 or something.
Hgb down at 8.5 with transfusions every second week...getting a bit tired of it. But hanging in :)

good luck to you!
Comment
Cancel
2004810 tn?1365157211
Comment
Comment
Submit Comment
Avatar universal
"SVR rates were 76% for patients who underwent RBV dose reductions and 72% for patients who did not reduce their dose of RBV."

So would that indicate optimum RBV level dosing could be determined by HGB count?
Comment
Cancel
Avatar universal
Comment
Comment
Submit Comment
2135877 tn?1381864726
It is posts like this that make this forum so valuable to me.  I was just riba reduced an hour ago and was concerned.  Reading your post calmed me way down.  Thank you.
Comment
Cancel
2135877 tn?1381864726
Comment
Comment
Submit Comment
Your Answer
1084115 tn?1385232189
Answer
Know how to answer? Tap here to leave your answer...
Answer
Submit Answer
A
A
Recent Activity
406584 tn?1399591666
Blank
10356 commented on msdelight's status
9 hrs ago
3060903 tn?1398568723
Blank
Nighthawk61 commented on mishymoshymarcy's status
19 hrs ago
3060903 tn?1398568723
Blank
Nighthawk61 I DO NOT KNOW THE WORD FEAR... Comment
May 05
Blank
Weight Tracker
Track your weight over time
Start Tracking Now
Top Hepatitis Answerers
683231 tn?1438659664
Blank
Auburn, WA
317787 tn?1460223707
Blank
DC
163305 tn?1333672171
Blank
Rural Mural, CA
446474 tn?1446351282
Blank
San Francisco, CA
Avatar universal
Blank
1815939 tn?1377995399
Blank
Hepatitis C Community Resources