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http://www.eurojgh.com/pt/re/ejgh/abstract.00042737-200610000-00005.htm;jsessionid=FvvTfqhQTQN2yV5XjldG5pSvvJgRMjnnsGzxLJ1GyfsJLHCL2hWv!1057067369!-949856144!8091!-1
http://www.norml.org/index.cfm?Group_ID=3376
http://www.natap.org/2005/HCV/062705_01.htm
http://hepatitis-central.com/mt/
My doctor doesn't agree with the above statement. He and I had a conversation about mj 2 weeks ago. He told me that it will not hurt my liver, and if it's what I need to "take the edge off" during treatment then by all means go for it.
I would ask your own doctor about it. Everybody here has different degrees of liver damage, so maybe what works for me and my liver, might not work for you.
-E
So we got hcv from behavior and maybe not doing some of those things today, your still doing things to get high and quoting web site or what ever you can find that agrees with your need to alter your self.
When your in the doctors office, dont you see all the drug companys reps leave thier samples ?
Next thing will be the miracle pill that will be pushed for everyone to take, just once a day and we will all live in a perfect world where we obey our trusted leaders.
God bless George Bush and the beautiful job he has done in Iraq.
Eveyone smoke pot and eat your pills because there is no need to feel it is much better to be altered and be convinced that is who we really are.
And what the hell, find a way to do tx again by same old behavior or just modified.
I agree with Lady E, that Mr Brian Fog and Ms MJ together are too much uufff.
Just smoke 2 hits if you need to eat and reduce nausea and sleep. Nothing else.
saludos
scuba
You take your car, and I'll take mine.
:)
So we got hcv from behavior
Excuse me, but maybe you got HCV from "behavior" but that isn't the case for many of us with HCV. Many got HCV from some source other than "bad behavior"
speak for yourself but please don't make broad statements such as this about "everyone" not everyone got HCV from some past bad behavior.
I agree with Kalio, speak for yourself, but don't make that kind of general comment about ALL of us.
We would all appreciate it if you, move, would stop insinuating that bad behavior is the only way to get HCV.
Enough said. Get the point, move.
miss
It sure seems like even more of you on here are even taking drugs today and I find all your talk about doing good and taking care {tx} of your selfs to be hypocritical.
Some one in this tread they smoked pot last night. So in this world of caring for your self and enlightenment you are so close to someone having pot ?
You give advice to others while the whole time your altered in some way ?
Of course your going to get pissed off and tell me to leave because I'm spoiling your high.
When I first got on here I thought what a great place but after some time I heard more and more of you are on drugs and advocate drugs, ads or pot or a drink a day won't hurt.
So if I am guessing right and 9 out of 10 got hcv from behavior and your still getting high in some way then who the hell are you to give advice.
I'm just giving you information so you can make whatever choice you want to make on it.
Here's a link: http://www.natap.org/2006/AASLD/AASLD_07.htm
Here's basically the same thing minus the tables.
=======================
A recently published study found that medicinal use of cannabis can relieve side effects and help chronic hepatitis C patients stay on interferon-based therapy, thereby improving their chances of achieving sustained virological response.
However, based on other prior research, there is concern that frequent, heavy cannabis use may promote the development of liver fibrosis.
At the 57th annual meeting of the American Association for the Study of Liver Diseases, held last month in Boston, researchers from the University of California at San Francisco reported on a study looking at the association between cannabis use and severity of fibrosis in individuals with chronic hepatitis C virus (HCV) infection.
Between 2001 and 2004, the researchers interviewed 204 HCV-infected subjects enrolled through university and community sources, assessing demographics, risk factors for HCV, and use of cannabis and alcohol. Participants also received virological testing and liver biopsies, which were scored using the Ishak system (stages F0 to F6, from absent to severe fibrosis).
Results
A majority of participants (69%) were men, 49% were Caucasian, 21% were coinfected with HIV, most were low income, the median age was about 47 years, and for 70% the presumed route of infection was injection drug use.
The median lifetime duration and average daily use of alcohol were 29.1 years and 1.94 drink equivalents per day.
13.7% of subjects reported daily cannabis use within 12 months prior to enrollment, while 45.1% reported occasional use and 41.2% said they never used cannabis.
Fibrosis stage was as follows:
- F0 (absent): 27.5%;
- F1-F2 (minimal/mild): 55.4%;
- F3-F6 (moderate to severe): 17.2%.
Daily cannabis use (compared with occasional or no use) was strongly associated with moderate to severe fibrosis by univariate analysis (odds ratio [OR] 3.21; P = 0.020).
The same held true by multivariate analyses (OR 6.78; P = 0.003).
Other independent predictors of moderate to severe fibrosis were:
- lifetime duration of moderate to heavy alcohol use (> 2 and > 4 drinks per day in women and men, respectively; OR 1.72 per 10 years; P = 0.044)
- > 11 portal tracts (compared to < 5; OR 6.92; P = 0.021).
- Patient age was of borderline significance (OR 2.19 per 10 years; P = 0.064).
Daily cannabis use did not appear to be strongly associated with mild fibrosis (F1-F2) compared to no fibrosis (F0) in univariate or multivariate analysis.
Independent predictors of mild fibrosis were:
- HCV viral load (OR 1.86 per log increase; P = 0.009);
- 5-11 or > 11 portal tracts (compared to < 5) (OR 3.43, P = 0.002 and OR 10.4, P < 0.001, respectively);
Patient sex, race, age, duration of HCV infection, HCV genotype, HIV status, body weight, tobacco use, and lifetime alcohol use were not significantly associated with mild fibrosis in this study.
Conclusion
"Current daily cannabis use independently increased the odds of moderate to severe fibrosis by nearly 7-fold in persons with chronic HCV infection," the researchers concluded. "Our results indicate that HCV-infected individuals should be counseled to reduce or abstain from cannabis use."
11/14/06
References
J H Ishida, C Jin, P Bacchetti, and others. Influence of Cannabis Use on Severity of Hepatitis C Disease. 57th AASLD. Boston, MA. October 27-31, 2006. Abstract 211.
D L Sylvestre, B J Clements, Y Malibu. Cannabis use improves retention and virological outcomes in patients treated for hepatitis C. European Journal of Gastroenterology and Hepatology 18(10): 1057-1063. October 2006.
So what!
You act like it's the end of the world!
What do you REALLY care if some people smoke pot and some don't..it's no big deal.
Take a chill pill or whatever it is that YOU use when you need to take the edge off.
BTW, this is your last week of tx, right? I hope you are making it through ok.
_e
You can't just make up figures and expect that no one will challenge them, you have no basis for your info other than
"what you think" which is just a wild guess based on your personal experience. It does promote "stigma" around this illness to contend all people contract it through bad behavior.
It isn't true but you just keep repeating it over and over. I finally decided to say something because you seem intent on repeating this misinformation.
I don't think it matters HOW people contracted this virus anyway, all that matters is how they can improve their health now. You seem to be bent on proliferating the stigma of HCV by constantly making up these bogus "facts" about how people get this disease.
Anyone who had a blood transfusion or dialysis or a variety of other procedures in clinical settings prior to 1992 is at risk for this virus and should be tested. There is a wide variety of other modes of transmission in addition to these modes. What about vertical transmission, those who were given HCV at birth? You think new born babies also used drugs?
It is true that IV drug use or sharing needles accounts for a large portion ( 60% so just slightly more than half) of victims, but there are plenty of people you are lumping into your bogus figures.
You might want to read up on the most recent studies. They've been out for quite a while now and show a strong association between cannabis use and increased fibrosis for Hep C patient (7 fold with daily use, which is very significant.)
http://www.hivandhepatitis.com/hep_c/news/2006/091506_a.html
(Personally, I think it helps.)
"The median lifetime duration and average daily use of alcohol were 29.1 years and 1.94 drink equivalents per day. "
these subjects, like I said, were all not only smoking pot but they were daily drinkers and who knows what else they were doing. That makes their claim that marijuana is responsible for this increased fibrosis completely bogus to me. How can they say it isn't from daily drinking, a KNOWN cause of fibrosis?
This is what is wrong with many studies, they draw conclusions based on ridiculous assumptions from a study population that isnt even representative. Show me a study of non drinkers who use MJ occasionally that shows ANY damage to their livers. It can't be done, no such study showed this to be true. You can't discount the alcohol or blame MJ when you are dealing with study subjects who are also drinking heavily!
People always drag this study out and it is so blatantly flawed I don't know how they can even state that MJ caused this increase in fibrosis with a straight face.
Stick around!
If you want to call the researchers on this topic blatantly wrong, that's fine. I would rather consider the advice given to me by my doctor, who is a leader and expert in Hep C research and who has urged me not to smoke it because it has been associated with liver damage (and these are not old studies, Kalio, or research from morons.) Perhaps you think they're all just pulling this information outta their a** for the heck of it. I'm an old time druggie who would love to fire one up but won't because of the new information on it and because I don't want to chance it. It makes no difference to me who smokes and who doesn't. I'm just providing the most recent studies on it and relaying that my doc concludes.
Conclusion
"Current daily cannabis use independently increased the odds of moderate to severe fibrosis by nearly 7-fold in persons with chronic HCV infection," the researchers concluded. "Our results indicate that HCV-infected individuals should be counseled to reduce or abstain from cannabis use."
The studies do suggest that pot is bad for the liver. They are pretty clear. But these studies track long term use. So, yes, if you have a compromised liver best not to smoke Pot.
On the other hand, using pot or medical marijuana temporarily during treatment to combat severe sides such as anorexia and nausea, seems to have merit and a recent study suggested medical marijuana during tx increases SVR rates by increasing compliance.
So, on one hand, pot use isn't good for the liver, but on the other hand, using it temporarily on tx to help keep oneself on tx does seem to have merit.
On a personal note, my doctor suggested medical marijuana to me about seven weeks into treatment because of nausea, loss of appetite and weight loss. Pot doesn't agree with me, so I declined but the reason wasn't because I thought it would bad for my liver.
-- Jim
I said it would not surprise if 8 or 9. And even if it is only 6 out of ten that means 6 out of ten poeple on here SEEM to be stuck in the same old behavior and recomending it to others.
I was only 10 yrs old in 1970. To young to try to stop cops from beating heads, but during the start this latest world war {1990} I sure have done my part in making noise of peace.
And so when I go off {belive me, I have never been in a chat room} as I have in here, It is because after hearing so much of AD talk and pot and beer, it is my nature to stand up for how I see it and honestly I belive my view {though maybe not clear, but is a view un fettered by personal, emotoinal or drugged up sight} is right on.
I HAVE ONE SHOT TONIGHT THEN 6 DAYS OF RIBA. I HAVE USED THIS ROOM AS A POINT OF FOCUS and right or wrong if I get throw out then as Damien Rice says in one of his new songs "I squeez my grapes and drink my wine"
And farther more " **** YOU" and that comes from someone who did have deep depression and pain and all the rest {except the low blood stuff} and no ads, not to boast but the counter act all the mindless pushing.
I have did it by having people tell me its ok to express that in a safe place.
So if there's some one out there that wants to vent as they are going through tx instead of drugging up then write me tedyvona and I am on hotmail
Use non drinking subjects who have positive healthy lifestyles who smoke occasionally and access them. Notice no study using that participant model exists that says MJ causes increased liver fibrosis.
We are talking about using marijuana medicinally while on treatment as an antienemic and/or a pain killer. Clearly the virus is harder on your liver than a few puffs of pot to keep you on the tx to attempt to kill the virus. People on treatment who make the choice to use pot for nausea as opposed to some pill should not be worrying it causes liver damage ased on a flawed study. They should be trying to get through the tx in the least toxic way they can without having to cease meds due to sides.
I say that people on HCV meds garner the same benefits that chemo victims and AIDS victims benefit from (antienemic, pain control,and more)and the evidence does NOT support that MJ damages our livers.
This study is not of people who are sick, number one, number two it is people who have a host of other behavior issues (ie alcoholism) so it is flawed from the jump. That indicates to me a politically motivated study.
Be well,
-- Jim
You're stranded on a deserted island without food. Next ship wont' be by for another two months. Your weight loss has become quite serious, so serious that if you don't eat something soon you will risk malnutrition or worse.
Low and behold an empty barge washes upon the beach. In it you find a couple of months worth of cheese cake. Nothing else.
Only problem is you're not allowed to eat cheese cake. You have very high cholesterol and a history of heart disease. Studies suggest that eating a high-fat diet (like cheese cake) will accelerate the your arterial plaque build up and eventually lead to potentially another heart attack.
So, you have a big decision to make. A very difficult decision. Do you start with the Cherry Cheese cake or the chocolate? Personally, I'd go with the Cherry, but that's just me :)
Be well,
-- Jim
I have always suffered from anxiety its in my makeup as my mom and her mom also did and the tx made it even worse, Im so glad that I had a pill ativan that would calm me down and help me finish tx plus take care of my 5 children and 30 hours of work, plus it helped me sleep even if it was for only 4 or 5 hours a night.. belive me there is nothing natural about this tx, but i had to give it a try for my kids, and I dont think you have to be hurtful to people who might need some help to get through this unatural treatment.........
Kalio says (I've only read the first sentence of her post but was already laughing when I read it, and when I read her first sentence I laughed so hard I had to write something before I got too bogged down with too much rhetoric that I KNOW I'm going to read if I continue reading her post right now, so here goes.....) Kalio, now remember, OK? I still think you're wonderful no matter if we disagree on some things.
Kalio says:
"I contend a "study" such as the one you site is stongly supported (paid for) by people with an agenda to deny marijuana use to medicinal recipients."
lol - OK Kalio, do you also contend that all studies on Hep C treatment our docs are using to treat us are "studies" that are strongly supported (paid for) by people with an agenda, or do you save this bias for just pot studies?
Rev, et. al - ya'll are a riot! I'll get back later if I have time (if for nothing else but to laugh my a** off.) Best high I know of!
I gotta go take my phenergan now. I think I heard Kalio saying I needed to take it suppository style :)
There are many people who I appreciate and admire on this forum (hi, jim, nygirl, kalio, many others!). And I always like to pop in and see how folks are doing.
Although I understand that this is a venue in which people are free to post their opinions, I don't believe that it's ever been the intent of the creators of this forum to provide an outlet for the expression of opinions in such a nasty and vehement manner.
This is a topic that comes up pretty often, and every time, it invokes a barrage of accusatory-style opinions and proclamations on the morals of other patients...who, incidentally, are suffering with the same condition as the accuser. And I am deeply saddened when it comes down to something along the lines of "this is exactly the type of behavior that got you into this kettle of fish the first time...haven't you learned your lesson?"
Each patient is an individual who came to this crossroads in their own way. 40 percent of us (myself included) are not in ANY of the "risk groups"; no needle sticks, prior drug use, tattoos, et cetera. It is an unfortunate situation not to know how we got here...but it is what it is.
For the folks that have found themselves here through prior "bad behavior," I still value their opinions as equally as the "innocents." Everyone here is a patient, is in pain, and is doing their best to deal with their situation as best they can. I'm certain anyone here who has contracted Hep C through drug use or some other behavior that they themselves caused feels absolutely terrible. Why add to their burden by branding them an "ex-con"? And when I interact with anyone, I try to remember that my job here is to help carry the load...pat backs, give cyber hugs, pass on informational links, share tips for getting through tx.
This is something that often comes up in other hotly contested topics such as whether to treat or not treat, whether to use anti-depressants or not to, whether or not a glass of wine can be enjoyed post-treatment.
It makes me very sad to pop in to check on my old friends, the ones who helped me tremendously through my second go-around with treatment (you guys really bore my weight on your shoulders, even if you didn't realize it...I appreciate it so much...especially when I felt all along and uninformed and confused during my first attempt) and find that there are still small, bitter battles being waged among fellow patients.
Please lower your guns, stop slinging your judgmental barbs, and for once, find some compassion. People come to decisions on the use of cannabis, interferon, and alcohol through their own research and networking. They have to make the ultimate decision, and that's what they do. Many people make these decisions based on a physician's advice.
It is not all right to publicly flog people based on these life-altering decisions simply because they differ from what you might decide for yourself. You show your own ignorance and lack of compassion.
As for my views on cannabis, I used to be dead set against it. I was very judgmental of anyone who did drugs. In fact, I did everything "right." No drugs, no reckless behavior, whatever. I still ended up here. Mosquitos? Earrings pierced? Who knows? Does it even matter?
The funny thing is, cannabis got me through my second round of treatment. I have no regrets. My doctor recommended ADs. I did my research. I was honest with my doctor. He supported it. It's simply a decision I made after weighing all of the various articles and studies on BOTH ADs and cannabis, including all the biases on both sides.
There are many folks who wouldn't touch it with a ten-foot pole. It's not for everyone. I'm extremely reluctant to take any sort of AD. I have no problem with anyone else opting for it. Everyone is different. Everyone's body is different, responds differently. And everyone has a different comfort level.
The sad thing is, this whole slinging-of-arrows style discussion among some of us resulted from one patient openly seeking INFORMATION, looking for ALTERNATIVES to help them get through the difficult and trying period of treatment. This is exactly the format we should follow if we want an open and warm environment for patients to help one another; right? Which is why I pop in less and less often.
- Wasabi Pea
Once I was stranded in Arizona next to the Colorado with no food, just beer {even in a desertone can get what one wants, This was in a life time past} I searched and searched, I found a coke can and some rope and a piece if wire. In no time at all I was eating cat fish.
God or science minded did not leave us empty handed to say "Go forth, and alter your mind"
:) laughter is still a good medicine isn't it?
:0