tx question

[hisramblinrose]

If you  do treatment  in a trial and its not successful for you,can you still do the new treatment that is available?Just finding out about the cc gene and have taken the test.Rose

[willbb]

If you  do treatment  in a trial and its not successful for you,can you still do the new treatment.
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The short answer is " it depends"   on a number of factors.
1) Was there a chance  of you getting a placebo in the trial?
2) Is the trial results blinded and would you have to wait (possibly 18 months or so) for it to be unblinded?
3) If you did get the study drug,what type was it?
4) could there be possible cross resistance to one of the now approved drugs?(The data is still a grey area in this regard)
5) If you failed in the trial ,,why ..were you a null. or partial responder  or possibly you have a relapse or a breakthrough.?

These are all factors that need to be thought about before entering a  trial and questions to take up with a knowledgeable doctor.

On the other hand you may be one of the very many that have good success in a trial and all the above is moot.

Best ..
Will

[Advocate1955]

Well, you posted earlier that you have genotype 1a and very little liver damage.  I guess I would need to defer to those here on the forum who have been through previous trials, but I am pretty sure you would be able to treat later with either the new medication, if you were placed on a placebo, or triple therapy if the trial drug didn't work for you.  It's really important to study up on the trials and make sure you understand all of the specifics about any trial you are considering. Some seem to have more of a win/win aim, and others seem to be more of a gamble.
My husband doesn't have any first hand experience with a trial, so I can't speak about this with a lot of knowledge, but others on this forum have.
I can say that he probably would have enrolled in a trial if there hadn't been a good treatment option available and if there had been a trial available that he met the criteria for and seemed like a good trial for him.
You basically have 3 options since you have little damage:  1) wait until new treatment options become available with 6 month check backs with your hepatologist, 2) look for a trial that you meet the criteria for and that presents chances that you feel comfortable with, or 3) treat with triple therapy because you have genotype 1a and your chances of SVR are higher now with triple therapy than ever before.
Good luck with your decision making.