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1201433 tn?1328997637

vomiting up meds

what are you suppose to do if you vomit after taking meds, I treated last year but never had any issues with vomiting. I think there is a anti vomiting medication, could someone give me the name, and answer my ? thank you so much, I am only three days in. Stalion
Best Answer
1815939 tn?1377991799
I also am on Zofran for nausea and vomiting. I take 8 mg every 8 hours, usually about an hour before I take my meds. You will need a prescription for it. With Zofran, do not wait until you get nauseated. Ondansetron works by blocking the 5HT3 receptors that are found in the brain and gut. This prevents the nausea messages being sent from these areas to the vomiting centre. Ondansetron therefore prevents nausea, retching and vomiting that can otherwise occur following surgery or due to cancer treatments.  

http://www.netdoctor.co.uk/cancer/medicines/zofran.html

"How does it work?"

"Zofran tablets, syrup and injection all contain the active ingredient ondansetron hydrochloride dihydrate, which is a type of medicine called a 5HT3 antagonist. (NB. Ondansetron is also available without a brand name, ie as the generic medicine.) Ondansetron is used to prevent and treat nausea and vomiting that can be caused by chemotherapy or radiotherapy treatment for cancer, or by surgery.

Vomiting is controlled by an area of the brain called the vomiting centre. The vomiting centre is responsible for causing feelings of sickness (nausea) and for the vomiting reflex. It is activated when it receives nerve messages from another area of the brain called the chemoreceptor trigger zone (CTZ) and when it receives nerve messages from the gut.

Chemotherapy, radiotherapy and surgery can cause a substance called serotonin (5HT) to be released in the gut. This 5HT acts on the 5HT3 receptors that are found in the gut and causes nerve messages to be sent to the vomiting centre.

5HT released by chemotherapy, radiotherapy and surgery also activates the 5HT3 receptors that are found in the CTZ in the brain, causing further messages to be sent to the vomiting centre.

Ondansetron works by blocking the 5HT3 receptors that are found in the brain and gut. This prevents the nausea messages being sent from these areas to the vomiting centre. Ondansetron therefore prevents nausea, retching and vomiting that can otherwise occur following surgery or due to cancer treatments.

Ondansetron can be given by mouth (Zofran tablets or syrup), by injection into a muscle or vein, by drip into a vein (intravenous infusion), or by suppository (see the Zofran suppositories factsheet linked at the end of this factsheet).

What is it used for?
Preventing and treating nausea and vomiting caused by chemotherapy or radiotherapy for cancer
Preventing and treating nausea and vomiting following surgery."


16 Responses
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1201433 tn?1328997637
                                                                                                                                    You are right Deb vanilla ice cream seems to be working for me , and I was not eating much because of the nausea, eating liitle bits all day seems to help, also saltine crackers.
Helpful - 0
179856 tn?1333547362
Ice cream should be considered a medication on treatment and we should only have to pay copays!
Helpful - 0
1201433 tn?1328997637
                                                                                                                                      Sorry I was able to eat some ice cream with my last dose of Incevik last night , and was able to keep that down .I am going to call the doctor today ,to see if I can get a perscription. Thank you so much for all the advice , do not know what I would do with out this forum, and all of you good people!
Helpful - 0
446474 tn?1446347682
Thanks can-do. I will put it on my list to try.

Hector
Helpful - 0
Avatar universal
Hi Hector, Doctor Kwo gave me Phenergan, that was the only thing that worked really good for me.......... Good luck
Helpful - 0
446474 tn?1446347682
Thanks!
I have to try something different this time.

H
Helpful - 0
1815939 tn?1377991799
It is too bad that Zofran quit working for you, Hector. I know it does not always work for all people. It is possible that the intravenous Zofran works well for you but the oral does not. I really hope you can find something that works for you because being nauseated is so miserable, and spinning is even worse.

I have also found that I dare not go too long without food, even when I feel nauseated, and even when taking Zofran, because it makes me more nauseated to be without food for very long. I

I think the antinausea medication you are thinking of (that comes in a patch) is scopalomine. It is an antiemetic. People often use it for motion sickness, like when they go out on a boat on the ocean.  I don't know if it would interact with the drugs we are on. (It seems someone on the forum was on it during treatment.) However, it might work for you. I also don't know if it would be strong enough to work during chemo but it might work afterwards.It is something to think about and ask your doctor about.

http://www.drugs.com/mtm/scopolamine.html

Here is a list of some other antiemetcics. I don't think I would take some of them but at least there are some choices that a person can read up on:

http://www.drugs.com/condition/nausea-vomiting.html
Helpful - 0
446474 tn?1446347682
Hi all.

Thanks for the info on Ondansetron, pooh.

They gave Ondansetron to me by IV after my liver cancer chemo treatment and the stuff worked wonders. Within seconds the urge to vomit just disappeared. Now I have the pills and for some reason they don't seem to work at all.(!) I try the ginger too. Minimal relief at best. The best thing for me is just eating a little food. I know it sounds strange but that is all that works. Meanwhile 8 weeks after TACE chemo I still get so nauseous for hour after hour I can't do anything because my head is almost spinning and I find I can't really think when I am that nauseous.....Maybe am pregnant? Pass the ginger ale and crackers!!!

I heard there is a med that comes in a patch that is support to work?

I have another chemo treatment for a 2nd liver tumor coming up on the 22rd. Anyone have any ideas, suggestions?

Thanks all!
Hector

Helpful - 0
Avatar universal
As others above said, my husband used Zofran, drank ginger tea, ate candied ginger (available in Asian markets), and ate raw ginger root to help with nausea.
Best wishes on feeling better.
Advocate1955
Helpful - 0
163305 tn?1333668571
Another good thing for nausea is ginger. You could try ginger tea with your meal, or use those ginger chews or even ginger ale.

Good luck.
Helpful - 0
179856 tn?1333547362
Sorry baby, I only did SOC...but I'd try and use a stocking to see if I really lost them. Yeah, I'm weird and obsessive..but you've known me for years so mo shock. ;)
Helpful - 0
1815939 tn?1377991799
I will try again. My computer is acting up.

I was constantly nauseated and very bloated before I got on Zofran. I also vomited a 3-4 times. After the first time I tried to keep a large bowl near me so I could vomit in that (gross, I know). Then I meticulously inspected the contents of the bowl to be sure there were no pills in it (even more gross, I know). If it was hours after taking the pills I did not do this but if it was soon after, I did. Of course, if they were already dissolved then there was no retrieving them. I never found any pills, but I also did not vomit but a few times about 2 months into treatment. Then I got the Zofran and felt better almost immedicately.

One tip. Brush your teeth before you eat and take your pills. Floss after eating. I found that brushing my teeth after eating and taking the pills really triggered my gag reflex which would not shut off until I vomited, which happened pretty quickly, lol.  

I hope you get some relief. That nausea and the vomiting make a person miserable.
Helpful - 0
1815939 tn?1377991799
A
Helpful - 0
1747881 tn?1546175878
Nausea was the worst side effect I had from incivek, I was on promethazine but it stopped working very well towards the end of incivek.
Lots have used the zofran and had good results.
Helpful - 0
1747881 tn?1546175878
Zofran (ondansetron)
Helpful - 0
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