Aa
A
A
Close
Avatar universal
what is hep c genotype 1a grade 2 stage2 mean
Hi
new to this site what does what is hep c genotype 1a grade 2 stage2 mean thank you
                                                           George251
Cancel
5 Answers
Page 1 of 1
184420 tn?1326743408
same stats as me, excpet for the geno my is unknown...

liver damage is indicated by grade and stage

stage 0 no damage all the way up to stage 4 cirrosis

there are also 6 or so know 'genotypes' type 1 is the most common in the USA and the hardest to treat also only 55% or so clear with the current SOC (standard of care) tx (treatment) interfuron and ribavivarin

Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
Genotype refers to the genetic make-up of an organism or a virus. There are at least six distinct HCV genotypes identified. Genotype 1 is the most common genotype seen in the U.S. HCV is an RNA virus related to the flavivirus family.  RNA viruses are genetically less stable than DNA viruses and are prone to mutate during replication.  It’s a common misconception that hepatitis C is just one virus, but in reality (as a result of mutation over hundreds of years), it’s a group of very closely related strains.  They are similar enough to be called HCV, but based on genetic differences, they can be classified into distinct groups called genotypes.
1a - mostly found in North & South America; also common in Australia

1b - mostly found in Europe and Asia.

2a - is the most common genotype 2 in Japan and China.

2b - is the most common genotype 2 in the US and Northern Europe.

2c - the most common genotype 2 in Western and Southern Europe.

3a - highly prevalent here in Australia (40% of cases) and South Asia.

4a - highly prevalent in Egypt

4c - highly prevalent in Central Africa

5a - highly prevalent only in South Africa

6a - restricted to Hong Kong, Macau and Vietnam

7a and 7b - common in Thailand

8a, 8b & 9a - prevalent in Vietnam

10a & 11a - found in Indonesia

“Stage” is the amount of fibrosis (scaring) detectable by biopsy…
from stage one (mild) to four (cirrhosis). Fibrosis is scar tissue that forms as a result of chronic inflammation and/or extensive liver cell death. Your health care provider uses the amount of fibrosis in your liver as one way of evaluating how quickly your disease appears to be progressing. knowing when you were initially infected with HCV is a great help in determining your rate of disease progression.

The Stage is assigned a number from 0-4:
• 0 = no scarring
• 1 = minimal scarring
• 2 = scarring has occurred and extends outside
the areas in the liver that contains blood vessels
• 3=bridging fibrosis is spreading and
connecting to other areas that contain fibrosis
• 4=cirrhosis or advanced scarring of the liver

“Grade” is the amount of inflammation, which is caused by the activity of the virus. Generally speaking, inflammation is the precursor to fibrosis.
The Grade is assigned a number based on the degree of inflammation, which is usually scored from 0-4 with 0 being no activity and 3 or 4 considered severe activity. The amount of inflammation is important because it is considered a precursor to fibrosis


Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
184420 tn?1326743408
maybe i am a 1c then?

lol

Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
Even though they can't put a tag on you, we still love ya!!
Trin
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
184420 tn?1326743408
ty Trin...poor old untypeable me...

LOL

it is funny even though my dr's think its strange they are not like overly concerned about it, they just consider me a '1 something' ... so i guess i wont worry about it either... i always knew i was 'special'

haaa
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Your Answer
Avatar universal
Answer
Do you know how to answer? Tap here to leave your answer...
Answer
Answer
Post Answer
A
A
Recent Activity
Avatar universal
Blank
317787 tn?1473362051
Blank
Dee1956 Meegy 172 days!! Coincidenc... Comment
Dec 01
406584 tn?1399591666
Blank
10356 commented on stilltrying1965's status
Dec 01
Blank
Weight Tracker
Track your weight over time
Start Tracking Now
Top Hepatitis Answerers
317787 tn?1473362051
Blank
DC
163305 tn?1333672171
Blank
Rural Mural, CA
446474 tn?1446351282
Blank
San Francisco, CA
Avatar universal
Blank
1747881 tn?1358189534
Blank
Greeley, CO
2059648 tn?1439770265
Blank
Hepatitis C Community Resources