Look into Alinia, it's a drug already on the market that's used for parasites (of all things). Prelim results show it is a powerful HCV antiviral (for geno 4 for now, but should work for other genotypes too), with very minimal side effects. Too early to say if it's really all that, but if I were in your shoes right now I'd be looking into harrassing my doctor into prescribing it to you (like yesterday)...especially if you plan on going 72 weeks. It may turn out to be a salvation that's already sitting on the pharmacist's shelf. Good luck!
The 72 week protocol is for people who are detectible at week 12 but non detectible by week 24.
If you're detectible at week 24, you almost have no chance of SVR, so doctors in the know will tell you to stop treatment.
That doesn't mean you won't get SVR -- just that you won't get to it with 72 weeks of your current treatment regimen.
I'll keep my fingers crossed that your're UND by week 24, but if not, please see another doctor (def a hepatologist) before continuing any further.
All the best,
-- Jim
Wow, that was too much trading for one sitting. A lot of info.
It all boils down to read, be informed, go with your gut. Treatment is a personal decision.
I made a stupid, uninformed choice 37 years and after having quite a wonderful life and looking forward to more I was hit with this dx in 2002. Stage2 grade 3. I was told SVR was a 30% chance and since I had the disease for 30 years + it seemed like a good idea to watch how it progressed. Well March 07 Biopsy said stage 3 grade 3/4, I decided to treat. I am at week 20 and still not UND. I am hopeful, though some day's I feel " I am in deep doodoo! Tx. hasn't been easy, and "if " I am finally UND, I plan to push for the 70+ weeks. If I am not, I will enjoy being off tx.for awhile and regroup. Life sometimes throws us a curve ball. I am addicted to my own personal hope, to be without it would be very depressing!
Teri
Valtod: 1. Incompetent individuals tend to overestimate their own level of skill.
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I've been to the very best doctors and to some very so-so doctors. What I've found (dermatologists excluded) is that the very top dogs are the ones that admit they don't know a lot of the answers. They are also the ones that invite patient input, listen to the patient, and actually let the patient make treatment choices. The so-so ones tend to be autocratic and it's either 'my way or the highway'. Dermatologists tend to fall into the latter camp, even the very good ones.
-- Jim
Mre: Alright already, lets put a fork in it!! IT'S DUN!!
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Who was the first that said, "it ain't done until I said it's done"...anyway...
We seem to agree on the word "Whiners". Actually, the word amuses me now, but while on treatment (that riba does make things worse) it bothered me alot, and I assume also bothers others a lot, for all the adjectives you used and more. I used the word here in a satirical sense, but unfortunately, some here still use it in that same mean spirited way, and ironically, some of them are treating. All I can say to them is that until you walk in the shoes I walked in during treatment, then shut the f*ck up. Nuff said on that.
Where was I...well, let me skip to the end since this is getting old and I got a good movie on freeze frame. No, I didn't jump to the net when I found out I had Hep C, cause it was 1969 and not net. It was called chronic persistent hepatitis then and without the net, you really just talked to your doctors about it. I was lucky that I had the very best then although it turned out they didn't know all that much back then. But when I did find out I had Hep C, around when it was discovered, I did check out the net for a few weeks and found very little worthwhile at that point. I still relied on my doctors who told me that treatments were "barbaric", failed most of the time, and to wait. That was probably in the monotherapy days.
Like I said, the next time I popped back into the net was when I started treating. On day one, I didn't know a PCR from a PCP. By day seven I had scoured the net and medical libraries and read all of Lindahl's work. On day 8 I changed doctors and asked for high dose riba and double-dosing. Yes, I ended up in the ER at week 2, but it wasn't for lack of trying. I tend to procrastinate, but once I get going I get going. I should also note that at the time I was incorrectly told I was between stage 3 and stage 4. Now I'm DUN.
-- Jim
"All Nature is but Art unknown to thee:
All chance direction,which thou canst not see:
All dischord,harmony not understood:
All partial evil,universal good:
And spite of Pride,in erring Reason's spite,
One truth is clear,Whatever is,is right." Alexander Pope