I got a Robo call from Costco yesterday to destroy or return the suspected source of the Hepatitis A outbreak, which is Townsend Farms Organic Antioxidant Blend frozen berries purchased from Costco stores.
When I was diagnosed with Hep C back in 1999, my GP insisted I get Immunized and get vaccinated for Hep A and Hep B. I think I had 2 for Hep A and then series of 3 for Hep B.
I believe I was told the immunization was for life. I should be OK right? I will throw the rest out. Horrible thought since I have Hep C to be exposed to Hep A. I'm 6 weeks post Gilead trial. Hope this doesn't screw up my UND and possible SVR.
Hepatitis A is one of the most common vaccine-preventable infectious diseases in the world. Effective vaccines against hepatitis A have been available since 1992, and they provide long-term immunity against the infection. However, there is no worldwide consensus on how long protection will last or whether there will be a need for hepatitis A virus (HAV) booster vaccinations in the future. In most countries, booster-vaccination policy is guided by manufacturers' recommendations, national authorities, or both. In June, 2002, a panel of international experts met to review the long-term immunogenicity and protection conferred by HAV vaccine in different population groups. Data have shown that after a full primary vaccination course, protective antibody amounts persist beyond 10 years in healthy individuals, and underlying immune memory provides protection far beyond the duration of anti-HAV antibodies. The group concluded that there is no evidence to lend support to HAV booster vaccination after a full primary vaccination course in a healthy individual. However, further investigations are needed before deciding if boosters can be omitted in special patient-groups.
You will be be fine... and no it will have no effect on your SVR, so just pass that Xanax over here....:)
For us on the forum with hep C...we should be vaccinated against both hep A & B to prevent further damage to the liver.
From the CDC...
How long does Hepatitis A virus survive outside the body?
"The Hepatitis A virus is extremely hearty. It is able to survive the body’s highly acidic digestive tract and can live outside the body for months. High temperatures, such as boiling or cooking food or liquids for at least 1 minute at 185°F (85°C), kill the virus, although freezing temperatures do not".
"For us on the forum with hep C...we should be vaccinated against both hep A & B to prevent further damage to the liver."
Thanks for posting this reminder for all of us on this forum.
Many, especially old IV drug users might have been exposed to Hep A and Hep B and their immune system have already created the antibodies. If you have been tested and have the antibodies you are protected from future exposure.
When I was tested back in 1999 I did not show exposure and did not have the antibodies. Thus my doctor gave me the vaccinations which came in a series. Hep A was 2 shots 6 months apart. Hep B was 3 shots, 2nd was 1 month later,and the 3rd was 6 months after the 1st shot.
All on this forum should know their antibody status of Hep A and Hep B.
I'm so glad I've been protected from this recent exposure from organic berries.
Anyone who was vaccinated for A & B need to get revaccinated every 10 years. That's what my hepatologist told me as well as the ER I worked at when I first got the shots.
How it's done here. 3 shots. 2nd shot 3 months after 1st shot.
3rd shot 3 months after 2nd shot.
And be prepared to do it again in 10 years. Did first series of shots in 1992. Then again in 2002. Then again in 2012. What can do posted about stating that the series "protective antibody amounts persist beyond 10 years in healthy individuals".....that's the key word....healthy individuals. If you have HCV you are not healthy. May look it, may feel it...and this can go on for years...why chance it...isn't one hepatitis enough to deal with.?
I finished my vaccinations in 2000. Well over 10 years ago. I have not been given or recommended a booster. Humm? I know during physical a couple years back my doctor remarked that my antibody levels for Hep A and B were still very strong. This is obviously something that can be monitored? Maybe if antibodies is over certain level my my doctor felt I didn't need 10 year booster?
I know if I would have been exposed to A or B and I developed the antibodies naturally then I would not have ever needed to be vaccinated at all.
I'm going to call my doctor Monday just to make sure I'm OK. .I'm going to search the web about booster requirement now. Does anyone else have experience with required 10 year booster for Hep A and B?
I just found this link above. My hepatologist has probably been monitoring my antibodies. This article recommends serological testing to monitor antibody levels for immunocompromised, elderly and occupational risk groups..
Basically the above link says:
Additional vaccine recommend if anti-HAV titers of <33 mIU/mL)
Anti-HBs level is <10 mIU/mL.
It also says additional research is needed. Heart_in_the-keys since you are a healthcare worker and subject to constant exposure your hepatologist recommends every 10 years.
I'm still going to call my hepatologist on Monday to tell him I have been exposed to Hepatitis A in the last 10 days.
your probably right....about the monitoring....and maybe because I worked in the ER it was just a matter of fact...I was, even before I had cirrhosis, told to be revaccinated again every 10 years....have been asked several times in the last two years if my A&B shots were up to date so there must be some reason my hepatologist wants me to get them.
I applied for a week-end part-time job in the ER and they asked me if my inoculation's were up to date and I had to list them....A&B was one that was required. When I worked there before I was a EMT...now I will be unit secretary but you are still in a hospital/emergency room environment.
Hepatitis A vaccination is recommended for all children at age 1 year, for persons who are at increased risk for infection, for persons who are at increased risk for complications from Hepatitis A, and for any person wishing to obtain immunity. T
Persons who have chronic liver disease. Persons with chronic liver disease who have never had Hepatitis A should be vaccinated, as they have a higher rate of fulminant Hepatitis A (i.e., rapid onset of liver failure, often leading to death). Persons who are either awaiting or have received liver transplants also should be vaccinated.
Which Hepatitis A vaccines are licensed for use in the United States?
Two single-antigen Hepatitis A vaccines, HAVRIX® (manufactured by GlaxoSmithKline) and VAQTA® (manufactured by Merck & Co., Inc), are currently licensed in the United States. A combination vaccine, TWINRIX® (manufactured by GlaxoSmithKline), contains both HAV (in a lower dosage; see table) and Hepatitis B virus antigens. All are inactivated vaccines.
How long does protection from Hepatitis A vaccine last?
A recent review by an expert panel, which evaluated the projected duration of immunity from vaccination, concluded that protective levels of antibody to HAV could be present for at least 25 years in adults and at least 14–20 years in children.
Postexposure Prophylaxis for Hepatitis A
What are the current CDC guidelines for postexposure protection against Hepatitis A?
Until recently, an injection of immune globulin (IG) was the only recommended way to protect people after they have been exposed to Hepatitis A virus. In June 2007, U.S. guidelines were revised to allow for Hepatitis A vaccine to be used after exposure to prevent infection in healthy persons aged 1–40 years.
Persons who have recently been exposed to HAV and who have not been vaccinated previously should be administered a single dose of single-antigen Hepatitis A vaccine or IG (0.02 mL/kg) as soon as possible, within 2 weeks after exposure. The guidelines vary by age and health status:
For healthy persons aged 12 months–40 years, single-antigen Hepatitis A vaccine at the age-appropriate dose is preferred to IG because of the vaccine’s advantages, including long-term protection and ease of administration, as well as the equivalent efficacy of vaccine to IG.
For persons aged 40 years and older, IG is preferred because of the absence of information regarding vaccine performance in this age group and because of the more severe manifestations of Hepatitis A in older adults. The magnitude of the risk of HAV transmission from the exposure should be considered in decisions to use vaccine or IG in this age group.
Vaccine can be used if IG cannot be obtained.
IG should be used for children aged less than12 months, immunocompromised persons, persons with chronic liver disease, and persons who are allergic to the vaccine or a vaccine component.
CDC does not have official guidance to define all subgroups of persons recommended to receive IG.
IG is indicated for persons at increased risk of severe or fatal hepatitis A infection. These persons include adults older than 40 years of age, particularly adults 75 years and older, persons with chronic liver disease (e.g., cirrhosis), and those who are immunocompromised.
IG is indicated for persons with decreased response to hepatitis A vaccine. Based on available data such persons include those with HIV/AIDs, persons undergoing hemodialysis, recipients of solid organ, bone marrow or stem cell transplants, persons with chronic liver disease (e.g., cirrhosis), and other patients unlikely to develop an adequate immune response. Also, antibody response after a single dose of hepatitis A vaccine in persons older than 40 years may be reduced, but data are limited.
Immunocompromised persons generally are incapable of developing a normal immune response, usually as a result of disease, malnutrition, or immunosuppressive therapy. IG is indicated for patients who might include those receiving high dose steroids, chemotherapy, immunomodulators, and those who have primary immunodeficiency conditions. Clinical guidance should be obtained if the immune status is unclear.
Thanks, Hector. Your information was spot on. My doctor wanted me to come in for IG shot. Just got back to my office after getting this shot. He said the IG was just for extra security and 3 years ago my anti-Hav was still in good range so not to worry. Thanks to everyone, you eased my anxiety and gave me good advice.
Thank you for that information
I have to say I was afraid to get any vaccines after discovering HCV and my liver was bad I was afraid the vaccines would/could make it worse.
Guess I will get the vaccines now.
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