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SAM-e question
Anyone out there taking SAM-e? How much do you take and have you noticed any improvements?
you prob won't even see this cause it's about to be blipped off the page, but I tend to agree with you, I think I was taking too many supps, now I've trimmed down and it's better...
OH- I don't blame you for not taking AD's. It doesn't make sense to me to put more toxic meds into your liver. Good Luck with the SAMe!
GD - I know what you mean about taking so many supps. I finally just threw in the towel and don't think about it anymore. That's one of the reasons I decdided to take the tx. Didn't want to take all the supps the rest of my life. Some are OK, but not ALL of them.
GD - I know what you mean about taking so many supps. I finally just threw in the towel and don't think about it anymore. That's one of the reasons I decdided to take the tx. Didn't want to take all the supps the rest of my life. Some are OK, but not ALL of them.
Interesting info on the red wine extract - in keeping with the mentality of getting your nutrients right from the source instead of a supplement - do you think maybe we'd all benefit from chugging down the red wine? Thoughts please?
BTW - I do take the resveratol - and the sam-e - and, it seems, about every other expensive supplement known to mankind.....
BTW - I do take the resveratol - and the sam-e - and, it seems, about every other expensive supplement known to mankind.....
For a while I was so nausous I didn't want to swallow anymore pills. However, I've been taking Omega 3 fish oil and lipoic acid, the whole time. Now I'm taking Gota Kola for helping dissolve the scar tissue ( cirrhosis). I just ran into some encouraging info about Sam-e helping build cells and reduce depression. Seeing my doc just gave me a script for an AD, which I won't take, it sounds like the perfect solution.
Thanks everyone.
Thanks everyone.
dragon heart tea huh? that's good to know...you know, other people don't get that ampy on it (not the jitters, just ampy, a little wired) but I haven't heard that from anybody else really, so it might not do that to you, just me, I have a really sensitive system, I'm glad to know there are some fellow supps takers on here like Grandma, a few others...you know I tried almost every one on the market, in different doses, and I found that a cheaper one, I think Natures Made? was just as good for giving me a little more energy, (you can buy it at most drug stores) and I tried more expensive ones too...I hang around a lot of other supplement heads who have hep c, and we share info...anyway, I think it's just as good and it's not too expensive...you might like it, it might pick you up a little...I hope so...
As far as the resveratrol, I know a lot of people who are taking this too, I saw a news program on it tonight, and some older people were claiming that it made them feel more energy, etc...but could be placebo effect, I don't know...HR has been taking it for awhile now, and I know a few members here who take it....just made from grape skins, how bad could it be? ha ha...anyway, I think I'm going to try it in small doses...I'll ask my doctor...be well
As far as the resveratrol, I know a lot of people who are taking this too, I saw a news program on it tonight, and some older people were claiming that it made them feel more energy, etc...but could be placebo effect, I don't know...HR has been taking it for awhile now, and I know a few members here who take it....just made from grape skins, how bad could it be? ha ha...anyway, I think I'm going to try it in small doses...I'll ask my doctor...be well
I'm taking 400mg a day on an empty stomach for 3 years. Took the joint pain completely away. I think it helps with mood, too. Love it!
Grandma, Thanks. I read good things about it recently. I'm going to give it a try. My liver is worth more than some number in the bank.
FSG: Thanks for the warning. I will be aware incase I get the jitters. Jitters and riba rage, a sure way to drive my husband nuts.
I live in wine country and love wine with dinner. Sigh. I walk fast down the wine aisle in the grocery. But if I come back in my next life as a fat lab mouse, I'll go for the red.
LB: The Dragon Heart tea I got from alchemistlab.com has really done the trick for me. If I feel the itchies coming back, I make some immediately. Thanks for asking:)
FSG: Thanks for the warning. I will be aware incase I get the jitters. Jitters and riba rage, a sure way to drive my husband nuts.
I live in wine country and love wine with dinner. Sigh. I walk fast down the wine aisle in the grocery. But if I come back in my next life as a fat lab mouse, I'll go for the red.
LB: The Dragon Heart tea I got from alchemistlab.com has really done the trick for me. If I feel the itchies coming back, I make some immediately. Thanks for asking:)
I've been taking it off and on for years, it makes me kind of nervous..but many things register speedy on me, so it might not for you, I know many who take it, in fact I know many who take this too...and I'm wondering about it, this is expensive too...I"m not recommending to anyone, and there are caveats in this article, but it's interesting...as follows:
Obese mice on a high-fat diet got the benefits of being thin _ living healthier, longer lives _ without the pain of dieting when they consumed huge doses of red wine extract, according to a landmark new study.
It's far too early to know if this would work in people, scientists said. But several were excited by the findings, calling it promising and even"spectacular."
The study by the Harvard Medical School and the National Institute on Aging shows that heavy doses of the red wine ingredient, resveratrol, lowers the rate of diabetes, liver problems and other fat-related ill effects in obese mice.
Fat-related deaths dropped 31 percent for obese mice on the supplement, compared to fat mice that got no treatment. The mice that got the wine extract also lived longer than expected, the study showed.
And astoundingly, the organs of the treated fat mice looked normal when they shouldn't have, said study lead author Dr. David Sinclair of Harvard Medical School.
"They're chubby but inside they look great,"Sinclair said Wednesday afternoon."You have to pinch yourself to make sure that this is all real, but the study involved 27 different researchers each of whom had a Eureka moment."
Sinclair said other preliminary work still under way shows the wine ingredient has promise in extending the lives of normal-sized mice, too.
Sinclair has a financial stake in the research. He is co-founder of a pharmaceutical firm, Sirtris Pharmaceuticals Inc. of Cambridge, Mass., which is testing to see if the extract can safely be used to treat people with diabetes.
For years, red wine has been linked to numerous health benefits. But the new study, published online in the journal Nature on Thursday, shows that mammals given ultrahigh doses of resveratrol can get the good effects of cutting calories without actually doing it.
"If we're right about this, it would mean you could have the benefit of restricting calories without having to feel hungry,"Sinclair said."It's the Holy Grail of aging research."
Even though he called the work"tantalizing,"Dr. Howard Eisenson, director of the Duke University Diet and Fitness Center urged people not to get too excited.
"All of us who practice medicine have learned that we can't leap from studies in the lab _ particularly in lab animals _ to what will happen in humans,"Eisenson said.
Resveratrol, produced when plants are under stress, is found in the skin of grapes and in other plants, including peanuts and some berries.
The 55 resveratrol-treated obese mice were on a high-calorie diet _ what one scientist called a"McDonald's diet."Not only were they about as healthy as normal mice, they were also as agile and active on exercise equipment as their lean cousins, demonstrating a normal quality of life that was unexpected for such obese creatures, said study co-author Rafael de Cabo of the Institute on Aging.
"These fat old mice can perform as well on this skill test as young lean mice,"Sinclair said.
The only major body measurement that didn't improve _ aside from weight _ was cholesterol, and that didn't seem to matter in the overall health of the mice, Sinclair said.
The study is so promising that the aging institute this week is strongly considering a repeat of the same experiment with rhesus monkeys, a closer match to humans, said institute director Dr. Richard Hodes.
Hodes cautions that it's too early for people to start taking non-regulated resveratrol supplements because safety issues haven't been adequately addressed.
Sirtris Pharmaceuticals is working on a high-dose resveratrol pill that unlike unregulated supplements on the market now, would be used as a drug and require Food and Drug Administration approval, said company chief executive officer Dr. Christoph Westphal. And that development and federal approval is about five years away, he said.
Sirtris is aiming the research at diseases of aging, which includes diabetes.
Sinclair's results are so promising that he rushed the study into the science journal while the obese mice are still alive, not waiting several more weeks or months until they die. That raises some issues, including specific figures about mortality, but is understandable, said outside experts. The obese mice still lived past the median age for mice of their weight.
Even would-be competitors are praising the study.
"It's a fairly spectacular result,"said University of Wisconsin medical professor Dr. Richard Weindruch, who co-founded another biotech company that looks at the genetics of aging and drugs that could expand life spans."People will go to McDonald's and afterwards they'll do super-sized resveratrol."
"This is fantastic,"said Brown University molecular biology professor Stephen Helfand, who was the first reviewer for the journal Nature and not part of the team."This is a historic landmark contribution."
Helfand said he won't be taking red wine extract supplements _ but he has put his elderly parents on them. Such supplements are available at health food stores and on-line, but not at dose levels equivalent to what the mice in the experiment got _ roughly equal to 100 bottles of wine a day in humans.
Mice, he said, are good initial test subjects for human drugs because their bodies function similarly to humans in many ways. However, the differences between mouse and man can prove crucial, he noted.
Sinclair said he takes resveratrol supplements, but doesn't recommend it for others.
Resveratrol works by spurring activity and regrowth in cells'mitochondria, which Sinclair called"the energy powerhouses of the cell."
Some scientists, such as Weindruch and Hodes, worry that the research may encourage people to forget about their diets and wait for a red wine cure-all that may never come.
"It's not an excuse to overeat,"Sinclair said. But he added that for mice at least, this shows you can be"fat, happy, healthy and vigorous."
Obese mice on a high-fat diet got the benefits of being thin _ living healthier, longer lives _ without the pain of dieting when they consumed huge doses of red wine extract, according to a landmark new study.
It's far too early to know if this would work in people, scientists said. But several were excited by the findings, calling it promising and even"spectacular."
The study by the Harvard Medical School and the National Institute on Aging shows that heavy doses of the red wine ingredient, resveratrol, lowers the rate of diabetes, liver problems and other fat-related ill effects in obese mice.
Fat-related deaths dropped 31 percent for obese mice on the supplement, compared to fat mice that got no treatment. The mice that got the wine extract also lived longer than expected, the study showed.
And astoundingly, the organs of the treated fat mice looked normal when they shouldn't have, said study lead author Dr. David Sinclair of Harvard Medical School.
"They're chubby but inside they look great,"Sinclair said Wednesday afternoon."You have to pinch yourself to make sure that this is all real, but the study involved 27 different researchers each of whom had a Eureka moment."
Sinclair said other preliminary work still under way shows the wine ingredient has promise in extending the lives of normal-sized mice, too.
Sinclair has a financial stake in the research. He is co-founder of a pharmaceutical firm, Sirtris Pharmaceuticals Inc. of Cambridge, Mass., which is testing to see if the extract can safely be used to treat people with diabetes.
For years, red wine has been linked to numerous health benefits. But the new study, published online in the journal Nature on Thursday, shows that mammals given ultrahigh doses of resveratrol can get the good effects of cutting calories without actually doing it.
"If we're right about this, it would mean you could have the benefit of restricting calories without having to feel hungry,"Sinclair said."It's the Holy Grail of aging research."
Even though he called the work"tantalizing,"Dr. Howard Eisenson, director of the Duke University Diet and Fitness Center urged people not to get too excited.
"All of us who practice medicine have learned that we can't leap from studies in the lab _ particularly in lab animals _ to what will happen in humans,"Eisenson said.
Resveratrol, produced when plants are under stress, is found in the skin of grapes and in other plants, including peanuts and some berries.
The 55 resveratrol-treated obese mice were on a high-calorie diet _ what one scientist called a"McDonald's diet."Not only were they about as healthy as normal mice, they were also as agile and active on exercise equipment as their lean cousins, demonstrating a normal quality of life that was unexpected for such obese creatures, said study co-author Rafael de Cabo of the Institute on Aging.
"These fat old mice can perform as well on this skill test as young lean mice,"Sinclair said.
The only major body measurement that didn't improve _ aside from weight _ was cholesterol, and that didn't seem to matter in the overall health of the mice, Sinclair said.
The study is so promising that the aging institute this week is strongly considering a repeat of the same experiment with rhesus monkeys, a closer match to humans, said institute director Dr. Richard Hodes.
Hodes cautions that it's too early for people to start taking non-regulated resveratrol supplements because safety issues haven't been adequately addressed.
Sirtris Pharmaceuticals is working on a high-dose resveratrol pill that unlike unregulated supplements on the market now, would be used as a drug and require Food and Drug Administration approval, said company chief executive officer Dr. Christoph Westphal. And that development and federal approval is about five years away, he said.
Sirtris is aiming the research at diseases of aging, which includes diabetes.
Sinclair's results are so promising that he rushed the study into the science journal while the obese mice are still alive, not waiting several more weeks or months until they die. That raises some issues, including specific figures about mortality, but is understandable, said outside experts. The obese mice still lived past the median age for mice of their weight.
Even would-be competitors are praising the study.
"It's a fairly spectacular result,"said University of Wisconsin medical professor Dr. Richard Weindruch, who co-founded another biotech company that looks at the genetics of aging and drugs that could expand life spans."People will go to McDonald's and afterwards they'll do super-sized resveratrol."
"This is fantastic,"said Brown University molecular biology professor Stephen Helfand, who was the first reviewer for the journal Nature and not part of the team."This is a historic landmark contribution."
Helfand said he won't be taking red wine extract supplements _ but he has put his elderly parents on them. Such supplements are available at health food stores and on-line, but not at dose levels equivalent to what the mice in the experiment got _ roughly equal to 100 bottles of wine a day in humans.
Mice, he said, are good initial test subjects for human drugs because their bodies function similarly to humans in many ways. However, the differences between mouse and man can prove crucial, he noted.
Sinclair said he takes resveratrol supplements, but doesn't recommend it for others.
Resveratrol works by spurring activity and regrowth in cells'mitochondria, which Sinclair called"the energy powerhouses of the cell."
Some scientists, such as Weindruch and Hodes, worry that the research may encourage people to forget about their diets and wait for a red wine cure-all that may never come.
"It's not an excuse to overeat,"Sinclair said. But he added that for mice at least, this shows you can be"fat, happy, healthy and vigorous."
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