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220090 tn?1379167187

liver panel results

I have the liver panel results and they are normal except for a mild elevation of GGT.  This is the first time since 1970 that they have been normal!  GGT was 350 8 weeks ago.  Still waiting for the PCR, but this helps calm me down.

Alt   46
AST 45
ALP 56
GGT 82

18 Responses
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179856 tn?1333547362
YOU GO MISTER WHEW HOOOOOOOOOOOOOOOOOO

your first normal enzymes - that HAS to be a harbinger of GREAT news to come!

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Avatar universal
Sounds great Eric!
MO
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217229 tn?1192762404
Me too... I keep checking in to see... Holding my breath ----darnit - I'm turning BLUE... LOL!

But those scores are fabulous dude.

No wonder your body is going into a shock.

Love you!

Meki
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208764 tn?1249429657
Eric,

You're looking good! 1/2 the way to SVR it seems that you're going to make for sure and gives me hope too. Thanks for your hard work and great attitude. Let me know when we're going to rent a 40 footer and go sailing in the gulf!!!!

Thanks,

Scott
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412873 tn?1329174455
Yay!  Happy for the good news......the best is yet to come!

Best to you,

Izzy
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476246 tn?1418870914
That looks really positive! My prayers are with you waiting for the PCR.

Marcia
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Avatar universal
good for you!!!  great news!

w.c. missy
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250084 tn?1303307435

Your going to be UND! I keep checking in here in a rush (back to work, life, busy) to see if your results are back yet!

Great on the LFT's ! The best new's is next! :)

LL
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446474 tn?1446347682
Eric,

It looks like your liver likes the treatment. I almost forgot what real (norm!) numbers look like. Nice to see 2 digits. Keep up the good work! I'm hoping your HCV RNA is looking just as good!!!

From AASLD - "LABORATORY GUIDELINES FOR SCREENING, DIAGNOSIS AND
MONITORING OF HEPATIC INJURY'

Gamma-Glutamyl Transferase:

Gamma-glutamyltransferase (GGT), a membrane bound enzyme, is present in decreasing order of abundance in proximal renal tubule, liver, pancreas (ductules and acinar cells), and intestine. GGT activity in serum comes primarily
from liver. The half-life of GGT in humans is about seven to 10 days; in alcohol-associated liver injury, the half-life increases to as much as 28 days, suggesting impaired clearance.

In adult men, a single reference range is adequate between the ages of 25 and 80. Although upper reference limits are approximately 2 fold higher in those of African ancestry, information on racial characteristics is not commonly provided to laboratories; it would thus be difficult for laboratories to report values with the appropriate race-based reference interval. In women and children, GGT upper reference limits increase gradually with age, and are considerably lower than those in adult men. Separate reference limits should be established for men and women, and for different age ranges in women and children. In children, this will probably require a cooperative effort of laboratories to obtain
adequate numbers of specimens from healthy children. GGT is slightly more sensitive than ALP in obstructive liver disease. GGT is increased an average of 12 times the
upper reference limit in 93-100% of those with cholestasis, while ALP is increased an average of 3 times the upper reference limit in 91% of the same group. GGT appears to increase in cholestasis by the same mechanisms as does ALP. GGT is increased in 80-95% of patients with any form of acute hepatitis.

Patients with diabetes, hyperthyroidism, rheumatoid arthritis and obstructive pulmonary disease often have an increased GGT; the reasons for these findings are largely obscure. After acute myocardial infarction, GGT may remain abnormal for weeks. These other factors cause a low predictive value of GGT (32%) for liver disease. The International Federation of Clinical Chemistry method described by Shaw is used by most laboratories. Precision with activities less than one-half the upper reference limit is about 10%; at about twice the upper reference limit, it is closer to 5%. Performance goals for GGT are primarily based on biological variation, with total error tolerance limits of approximately 20%. These are adequate for clinical purposes, given the limited clinical utility of GGT measurements.

Cheers!
Hector
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Avatar universal
it really does look good, jm
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220090 tn?1379167187
thanks for the support - as always!
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220090 tn?1379167187
GGT is found on the cell surface on all cells, with particularly high concentrations in the liver, bile ducts, and kidney.

In my view, not a very important test.

From Wikipedia:

Gamma-glutamyl transpeptidase
GGT is found on the cell surface on all cells, with particularly high concentrations in the liver, bile ducts, and kidney.

Clinical significance

Since serum GGT mainly comes from the biliary system, it is a sensitive test for liver function, especially in biliary obstruction.

Its level in the blood may be tested for, as an elevated level may indicate an abnormality in the liver, though this can be caused by a number of conditions
Helpful - 0
146021 tn?1237204887
I'm glad that the labs look better than 8 weeks ago.
I have to show my ignorance but, what is the GGT? It doesn't sound familar to me.
It looks a lot better than it did 8 weeks ago, inspite of being elevated.
Bug
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276730 tn?1327962946
Goood Luck Andiamo.
The very best always.
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Avatar universal
Something good must be going on!
Best of Luck to you!
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Avatar universal
Yay!!!!  Anything that calms you down is good and these are good results.  Hang in there til the PCR, Eric!!  Keeping you in my thoughts!!

Trish
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Avatar universal
I am very encouraged. I think cautious optimism is a reasonable response. I wish you the very best. Mike
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320078 tn?1278344720
that is great!  hopefully the other test come back good!

peace
rita
Helpful - 0
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