First I would like to thank you for taking the time to advise us so well on this forum. It is always a joy to read your replies. You were so kind to answer my questions about treatment for geno 3 a few months ago and I have now been treating for 5 weeks and run into a problem.
I received my 4 week PCR result and to my great disappointment, the result was still detected with a sensitivity test of <80 IU/ml.
45 yrs old, female, half African American half Swedish
56 kg, 800mg Rebetol - 180mcg Pegasys
could not have biopsy due to slow coagulation factor,
but no cirrhosis or other irregularities of any organs where seen on two ultrasound scans, even though it looks like I probably have had it for ca 25 years
Baseline VL 1.3 million
4weeks <80 detected
I live in Copenhagen Denmark and am being treated at Denmark's main hospital by Dr. Mette Kjær and Dr. Mette Rye Clausen at the Rigshospitalet.
After reading the ACCELERATE study, I understand that my shot at SVR with 24 weeks of treatment might just have dropped from 90% to 49%, or somewhere in between, due to not reaching RVR4.
A few months ago you advised that one should add 24 weeks of treatment to the time of EVR. I will have my next PCR at 8 weeks and was discussing with my Doctor to extend to 32 months, if EVR8. (which seems very likely, as I am almost UND)
Here they usually do not extend tx, but she is open to the fact to prolong, due to me being partially Afro American and also being concerned because of that. She just does not have any studies to back up my suggestion and is looking to find something. I have two questions:
1. How would you suggest we proceed,according to the facts I presented. On a note, they will not do another PCR before week 8, so I will not know when I cleared between 4 and 8.
2. Do you have any written papers you could direct me to, to back up the theory of prolonging 24 weeks after EVR. Any reports written by yourself or your university or hospital.
My hepatologist has just been to The Liver Meeting and was going to get some info on extending genotype 3 and on treatment of African American patients, as I am half African American. I will have a meeting with her Tuesday 18th and would be so thankful, if I had some input from you to bring to her.
This site complies with the HONcode standard for trustworthy health information.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.