Indicaters for Chronic HepatitisB activity

Posted By Santosh Shah on April 08, 1999 at 12:30:53:







Dear Sir,
I am an engineer, writing to you from Ahemedabad, Gujarat a state in India, Asia. I have visited your website and have read the old querries.  However my case seems to be a little different. I have been diaognised to have Chronic Active Hepatitis B. My case/test  history is briefly as follows.  Some of the tests may not be related to Hepatitis but still they have been presented for ready reference.
.

Date Test                  Results                           
11/14/92HBsAg(ELISA) Positive
HBeAg         Negative
SGPT         45units/ml
2/4/94 SGPT         53units/cc
SGOT         45units/cc
7/19/94 HBsAg (Human, West Germany)                 Positive
2/7/95 HBsAG (Elisa, Ranbaxy Diagnostics, India) Positive
2/25/95 Fasting Blood Sugar 89mg%
PPBS                 105mg%

4/21/95 Blood Serum Chemistry
Protein-T/Biuret (7.75 G/DL);  Albumin/BCG(4.50 G/DL);
        S. Globulin 3.25; A/G Ratio(1.4); Bilirubin- T/DPD
        (0.59MG/DL); SGPT (191.0 U/L); Alkaline Phosphate
        (104 U/L)
4/28/95 Lever Function Test
BT(Dukes method) (3m 30s); CT (Capillary Tube) (5m30s);
        Lee&White(7m15s); SGPT (137 Units/ml); Prothrombin index
        (80%);  Blood Examination Report   normal
5/2/95 Hepatitis Marker (ELISA)
HBsAg (46.51);  HBcAg IgM (0.191);  HBeAg (Negative);
        HCV(Negative) Abscence of antibodies to core antigen
        with presence of HbsAg suggests activity of B.Hepatitis
6/5/95 SGPT 104 U/ml
8/3/95 SGPT 75 U/ml
10/8/95 SGPT 40 U/ml
12/30/95SGPT 81 U/ml
4/9/96 SGPT 68 U/ml
6/25/96 SGPT 72 U/ml
8/9/96 SGPT 97 U/ml
10/28/96SGPT 76 U/ml
2/15/97 SGPT 98 U/ml       
4/9/97 SGPT 92.6 U/ml
5/29/97 SGPT 69.9 U/ml
8/4/97 SGPT 96.4 U/ml
10/1/97 SGPT 115.5 U/ml
1/7/97 SGPT 77 U/ml         
4/10/98 SGPT 63.2 U/ml
8/22/98 SGPT 63.7 U/ml   
11/27/98SGPT 54.2 U/ml   
9/2/98 Prothrombin Time Test (Patient Plasma) 11.0 Sec
          Control (Normal Human Plasma) 10.0 Sec
Bleeding Time 1 30
Clotting Time 6  20

My querries are as follows:
From the above trends of the various test results can it be
concluded that I have Chronic Active Hepatitis B?
On 4/26/95,  Gastroenterologist had advised us Interferon Therapy
with 60-70% clearance in 1 yr - upto 50% chance of reappearance &
would require retherapy. Clearance rate of  B+ is 2% per year.  
I had turned to  traditional medicines (Ayurvedic) as here they
are said to be more effective in gastric related diseases. Have  
things improved since 95 in Interferon Therapy?  How effective is
Lamiwudin?  Any chance of  CHB+ getting 100% cleared?
My  SGPT on 11-27- 98 is 54.2 which I understand is near normal
of 40. I am not taking  almost any direct fats in my diet. Is
SGPT the conclusive evidence of  the status  of the lever?  
Or in other words if  I keep my SGPT under control  lever damage
will be limited?  
I feel  very good when I take natural fat foods like
ground nuts and  roasted  grams. Would my taking  fats in  
natural form be harmful to the  lever?
After what period should I take lever function test.?
Would I have to keep away from fats life long?
Any specific advice on the diet?
My wife and son have taken vaccines. Any advice for them?
I know these are little too many questions. But I believe it is appropriate to ask an expert doc. all questions than to a general practitioner.
Thanks and awaiting your early reply,
Yours,
Santosh Shah









Follow Ups:


Re: Indicaters for Chronic HepatitisB activity HFHSM.D.-D.M. 4/12/1999
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