LIVER BIOPSY INTERPRETATION

Posted by COURAGEOUS on June 13, 1999 at 01:31:32
DEAR DOCTOR
    My name is Aamir and i am from Pakistan. I had a biopsy done last week i shall be grateful if you please interpret for me. The report is as under.
GROSS DESCRIPTION:
Specimen received fixed in formalin and consists of a core of tissue measuring 1.8 cm in length. Specimen submitted totally in one block.
MICROSCOPIC DESCRIPTION:
Section reveals a needle core of liver tissue with preserved lobular architecture. The portal tracts are infiltrated by variable moderate to dense chronic inflammatory cell infiltrate. Focal spill over of chromic inflammatory cell infiltrate into adjacent parenchyma is also seen, but there is no evidence of piecemeal necrosis. Some bile duct proliferation and mild fibrosis is seen. Mild kupffer cell hyperplasia is present. There is mild focal congestion of sinosides central vein is unremarkable. The hepatocytes reveal moderate patchy fatty changes. These appearances are of chronic hepatitis with focal activity and focal fibrosis.
MICROSCOPIC DIAGNOSIS:
CHRONIC HEPTITIS WITH FOCAL ACTIVITY AND FOCAL PORTAL FIBROSIS ( KONDELL SCORE  3)
End of report
I had also  a biopsy done three years before. I just want to know how much damage is done in these three years. its report is as under.
MICROSCOPIC DESCRIPTION.
Section shows core of liver tissue with some what maintained lobular architecture. The portal tracts are mildly enlarged and infiltrated by a moderate chronic inflammatory cell infiltrate and show fibrosis. The limiting plate is intact. There is no evidence of piecemeal necorsis. The hepatocytes show some balloning degeneration and focal moderate fatty changes with mild duffer cell hyperplasia. No granulomas are seen and there is no evidence of malignancy. These appearences are non specific ( ? Persistent Hepatitis)
MICROSCOPIC DIAGNOSIS:

LIVER BIOPSY : NON SPECIFIC
End of report
Looking for your early reply

  

Posted by Patrice on June 14, 1999 at 00:15:23
Hi Aamir, I am also anxiously awaiting a response from the doctor with info on your biopsy.  I had a liver biopsy 8years ago and was told that I have "autoimmune hepatitis" with early stages of cirrhosis. I have been on prednisone for 8years now.  But I have'nt had another liver biopsy, which I really think that I should have had another by now, to see if the cirrhosis has spreaded.  Coincidentally, my husband is also from Pakistan, I am an american tho.  He is from Karachi.  Are you taking prednisone for your liver disease.  How does it affect you working.  I am always tired.  I was just diagnosed with osteoporis of the spine and right hip.  I am 33yrs old.  I have children and find it very difficult to work and be a mom without always being so very tired.  I feel so guilty when I feel so tired.  Well hope to hear from the doctor and from you real soon.  Do take care.

Patrice

Posted by Courageous on June 14, 1999 at 11:07:31
Hello Patrice
Its good to know that u have some connection with my land. I am from Lahore and is 29. I dont have cirrhosis but my father died in april with this monster. i have a very mild hepatitis, i did biopsy three years back and now the second one just to see how much the demage done, but my doc told me the two biopsies are nearly same.
Praying for your recovery
Love
Aamir

Posted by HFHSM.D.-D.M. on June 27, 1999 at 18:06:00

Dear Aamir:
I appreciate the opportunity to review your two biopsy reports and to comment.  First of all, I am going to assume that you have hepatitis C because you have filed your question in that