Hello, I am a 52 year old 140 lb female. I am a Geno Type 1A with Grade 2 Stage 4 . When I started treatment on 2/1/08 my viral load was 12M, within 8 weeks of the triple combo I was undetectable. I took 180iu of peg (reduced to 135 after 4 weeks), 1000 Riba and 1000mg of R1626 (16weeks) I continued to be undetectable until I had to stop treatment due to dangerously low lymphocytes and CD3/CD4 on Nov 26 2008; after having done 43 of 48 weeks. On Jan 2nd the blood work showed I relapsed and my viral load was 4M. I would like to know how long I should wait to retreat. How should I retreat? I wonder if I had been able to take the full dose of the Peg if I would have had a better chance. The Prodrug affected me so badly that they had to reduce the Peg. I have not taken the R1626 since June of 08, it is now Jan 09 and my immune system is still affected
I would appreciate any advice or information you can share. My doctor said that it would be a waste of time to try 48 weeks of SOC since I took that however I really didn't 135iu is not 180 and 43 is not 48. I have been told that because I am stage 4 I will need to treat more aggressively or maybe longer. I am very confused and afraid.
I would wait as well with this one. This drug has had some bone marrow effects and they seem to last a long time. You may be able to qualify for a protease trial or one of the two proteases when they get approved in 2011. Certainly rushing to treat now would be a mistake. Take some time off and cure your liver, your marrow and your soul. then we can deal with this next year.
Thank you very much, I have been through a year from hell and everyone, family and friends are telling me I need to treat right now because of my transitioning to cirrhosis
Study doc not helpful. Thank you so very much!
Copyright 1994-2017MedHelp International.All rights reserved. MedHelp is a division of Aptus Health.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.