suppressive therapy with acyclovir is 400mg 2x/day.
the rates of acyclovir resistance are still the same as they were when the medication was first discovered for use with herpes over 25 years ago. No worries about resistance.
I recently had to take prednisone because of the severity of the "cold sores"
It always seems to clear up the breakouts a lot faster. Though, I do not likle the way it makes me feel at times. I have been taking the suppressive therapy while on prednisone (tappering down now).
I hope this will help sustain any other further outbreaks.