How many people have transmitted virus while on Valtrex?

[mystupidex]

I'm curious to know if anyone has transmitted HSV2 while on Valtrex daily?  I'd also like to hear from people who have stayed on Valtrex daily and their partner has remained infection free.  Also, is it true that the Valtrex study on tranmission may actually have better results since some of the people may have occassionally forgot to take their pill

[gracefromHHP]

You can read the whole valtrex and reduction in transmission study for free on the NEJM website ( jan 1, 2004 issue ).  Just register there and you can read it.

Yes, 2/3's or so of the folks who transmitted the virus during the study were not remembering to take their medication at least 80% of days.  Remembering to take it daily ups the odds of not transmitting to a partner even more.

I've never transmitted the virus to a partner since I"ve been on daily suppressive therapy. I use acyclovir most of the time - took valtrex for less than 1 year and stopped.

grace

[mystupidex]

Thank you very much for responding.  Do you always use protection too?  I take mine faithfully every day and may start breaking the 1 gm in half and move to twice daily to keep it my system.  Have you heard much from others on here about their luck with the anti-virals?  How often do you have breakouts?  I don't think I've had any "official breakouts" in the past few years.  I do get some tingling every couple months.  I have however noticed occassional small pimple-like single bumps that do not itch or tingle in pubic hair area or on my bottom.  Do you know what the likelihood is of those being a minor breakout?  Sometimes they get a white head on them.

[gracefromHHP]

I don't always use condoms.  I don't use them in long term relationships after a few months either.

I get about 1 ob a year while on suppressive therapy .  sometimes more if I have a lot of vaginitis issues going on.

next time you have one of your bumps you are noticing, try to be seen within 48 hours of its appearance for a lesion culture but they really sound like pimples or even infected hairs or something.

grace