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Avatar universal

I know it's nonesense

I'm 35 years old male I've never had cold sores before on  I met my European gf she's cold sore on her upper lip for 7 days & it was crusted.for the next 7 days I deep kissed her & we had protected vaginal sex after I came back home on I discovered an ulcer in the back of my mouth it was painless on the upper inner gingival margin  just above the last molar tooth with a little discomfort in my throat. I made hsv serology & the results came back as follows 13 days after exposure : All serology came back negative. I had a dental specialist looked up the sore after 5 weeks of exposure (the ulcer didn't heal completely) & she told me it's unlikely to be herpes. I consulted a dermatologist & she told me : With your proposed high risk factor it should be on your lips so it's unlikely to be herpes. I made serology after six weeks of exposure & it came back as follows : HSV IgG positive 106 U\ml - negative less than 20 U/ml - HSV 2 IgG : Negative 10 U/ml -negative less than 20 U/ml- my questions are : How likely is the false positive in the last serology ? I tried to know the kits the lab is using but in vain (I live in a middle east country) & should I repeat the test ? I know it's nonsense to ask since I was exposed to high risk but I hope to get some answers to ease my mind
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Avatar universal
Thank you very much for the clarification & much appreciated .
Helpful - 0
Avatar universal
I do not see the point of retesting. You may have an oral HSV1 infection from your youth. It is then virtually impossible to be reinfected in a different region. An oral infection is of no consequence. There is hence nothing additional that testing will help you with.

You may have outbreaks now and again, but this is unrelated to having a partner with oral HSV1.

The ulcer inside the mouth is most likely not herpes.
Helpful - 0
Avatar universal
The lab with the strong positive result : HSV 1 IgG 106 U/ml negative less than 20 U/ml informed me that they are using IFA & it's more accurate than ELISA that maybe used by the other labs ,how true this statement ? & if I'm infected long time ago probably during childhood is it possible that I'm reinfected & I develop recurrences from now on ? Shall I retest at the 3 months mark ?
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Avatar universal
Testing for HSV1 can be inaccurate, 1 in 10 infections can be missed.

With a strong positive for at least one test then for the time being I would assume you have HSV1.

However if this is the case, you have had the infection for a long time most probably. You have not been recently infected.
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Avatar universal
How % chances I haven't contracted HSV 1 based on my last test in your opinion? Thanhs
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Avatar universal
The positive result was my second test only HSV 1 IgG at 6 weeks & my 1st test at 13 days after exposure was negative HSV 1&2 both IgM & IgG , is the last negative result a good indicator ? Shall I put my mind into ease till the 3 months mark as I'm planning to do a full STDs tests as well?
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3149845 tn?1506627771
Confirmation would be at the 3 month mark but since 8 weeks would be a good indicator it should come back negative but the concern is your first test was a bit high.
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Avatar universal
My repeated test results : 49 days after exposure
HSV 1 IgM : 9 EU/ml  negative up to 100 EU/ml
HSV 1 IgG : 3 EU/ml  negative up to 20 EU/ml
HSV 2 IgM : 6.2 EU/ml  negative up to 100 EU/ml
HSV 2 IgG : 1.6 EU/ml  negative up to 20 EU/ml
Can I disregard the last positive result of HSV 1 IgG 106.6 U/ml Negative less than 19.9 U/ml?
Helpful - 0
3149845 tn?1506627771
If its a little bit high then could be a false positive so do retest to confirm
Helpful - 0
Avatar universal
One last question please, the last reading was 5 folds plus the cutoff isn't it conclusive for positive cause you said it's a LITTLE BIT HIGH ! Thank you very much
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3149845 tn?1506627771
I think that would be best.
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Avatar universal
So shall I repeat the test ?
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Avatar universal
So shall I repeat the test ?
Helpful - 0
3149845 tn?1506627771
Your first test was a bit high so i would lean more it is positive but up-ward of 65% of the adult population would also test positive for hsv1 oral as is quite common. Yes these test are quite reliable but do miss 10% of recent infection.
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Avatar universal
Thank you very much for the prompt response,
Do you think these test kits are reliable ? Considering my high risk do you think I still have a chance not contracting HSV ?
Helpful - 0
3149845 tn?1506627771
If you had one positive and one negative for hsv1 then retest.
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Avatar universal
Then shall I assume the results of 13 days after exposure : all serology negative as FALSE NEGATIVE ? Or shall I repeat the last positive test ?
Helpful - 0
Avatar universal
Yes it was specifically for HSV 1 IgG 106 RU\ml after 6 weeks in other lab & 13 days after exposure it was HSV 1&2 both IgM & IgG negative in a different lab. I've never experienced any outbreaks or cold sores in my life
Helpful - 0
Avatar universal
It does seem more likely than not that you already have HSV1, despite no living memory of cold sores. Most likely you acquired the virus in your youth. This is not uncommon at all.

Hence there appears to be no further risk of HSV1 infection. Avoid outbreaks and keep on with the kissing!
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Avatar universal
Important question... was the HSV IgG result of 106 Ru/mL result specifically for HSV1?
Helpful - 0
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