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Impact of antiviral medicines to HSV-2 igg results
Do you mind help me understand a bit more on Herpes blood test (HSV-2 igg results), particularly for patients showing positive herpes culture and symptoms (blisters, sores, etc.) at least a few years ago, but who have been taking antiviral medicines for sometime? Does it mean:
1.Such patients' blood test "HSV-2 igg" results may show negative?
2.If so, what percentage of those patients might show negative in blood test?
3.Is any of the blood tests (Western Blot, HerpeSelect, POCkit, etc.) less sensitive to the impact of the antiviral medicines, thus able to show that a patients is indeed herpes positive in a blood test?
By the way, is there any relevant research/studies or publications that you could share with me, or anybody else I could contact regarding this topic?
Hi Grace,
I have another question, need your help to understand.
Is it possible for the same person that HSV 1 or 2 IgG values are consistant in certain range, for example. the first two tests showed hsv2 IgG were all less than 0.2, and the third test showed the IgG number jumped to 0.73?
What are the possible reasons the value changed?
Thank you,
Renee
I have another question, need your help to understand.
Is it possible for the same person that HSV 1 or 2 IgG values are consistant in certain range, for example. the first two tests showed hsv2 IgG were all less than 0.2, and the third test showed the IgG number jumped to 0.73?
What are the possible reasons the value changed?
Thank you,
Renee
seroreversion happens but not a whole heck of a lot from what research we have.
does daily suppressive therapy cause a patient to test negative on repeat testing? no it does not. There is some evidence that it can slightly reduce igg values but it wouldn't turn a true positive into a negative.
so what do you do with patients who get retested later on and are negative? first ask them how they were originally diagnosed. some folks are still visually diagnosed as having hsv2 which is wrong about 1/3 of the time. others are just cultured and assumed hsv2 and not typed when in fact it could be hsv1 . still others are blood tested, have low positive results but they are never confirmed and they start suppressive therapy convinced they have hsv2.
there is a study I think by anna wald that is something along the lines of time to serconversion or something like that that covers this topic somewhat. I can't recall any studies specifically on seroreversion.
keep asking questions :)
grace
does daily suppressive therapy cause a patient to test negative on repeat testing? no it does not. There is some evidence that it can slightly reduce igg values but it wouldn't turn a true positive into a negative.
so what do you do with patients who get retested later on and are negative? first ask them how they were originally diagnosed. some folks are still visually diagnosed as having hsv2 which is wrong about 1/3 of the time. others are just cultured and assumed hsv2 and not typed when in fact it could be hsv1 . still others are blood tested, have low positive results but they are never confirmed and they start suppressive therapy convinced they have hsv2.
there is a study I think by anna wald that is something along the lines of time to serconversion or something like that that covers this topic somewhat. I can't recall any studies specifically on seroreversion.
keep asking questions :)
grace
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Herpes spreads by oral, vaginal and anal sex.
Herpes sores blister, then burst, scab and heal.
STIs are the most common cause of genital sores.
Millions of people are diagnosed with STDs in the U.S. each year.
STDs can't be transmitted by casual contact, like hugging or touching.
Syphilis is an STD that is transmitted by oral, genital and anal sex.
