SSRI affect on antibody IGG type-specific test

[help_me880]

Hi Terri,

I posted a question a few months back but it has closed, so I am posting a new one.  My test at 29 weeks (over 6 months) came back negative (<.90 for both types, specific #s not given).  

I was wondering if SSRI can have an impact on the antibody tests and cause a false negative.  For example I saw a study that HIV viral replication can be reduced by SSRIs.  Also read a study that MAOI can prevent/reduce HSV viral replication due to something involving the LSD-1 (http://insciences.org/article.php?article_id=7314).  I am not a technical expert on these studies, but was wondering if having started an SSRI (lexapro) about a month or so after the incident of concern could cause me to have a false negative this far out or if I should consider the 29 weeks (over 6 months) test to be conculsive.

Thank you

[Terri Warren, RN, Adult Nurse Practitioner]

No, SSRIs do not have any known impact on herpes antibody testing whatsoever.

Terri

[Terri Warren, RN, Adult Nurse Practitioner]

I don't think so, but having HIV could potentially impact a test because a person who is immunocompromised to the extent that an HIV patient on antiretrovirals are used, might not make antibody as well as a person not in that situation.  That's a guess.

Terri

[john220022]

Hi

Would HIV antiretrovirals impact a herpes antibody test?

[Terri Warren, RN, Adult Nurse Practitioner]

I would be very confident, yes.

Terri

[help_me880]

Thank you Terri.  I took a 36 week test - IGG type specific negative for both types.  (no exact #s given, just <.90)  Would you still be confident in the results despite the medicine (Lexapro)?