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Valtrex resistance

I had my first outbreak in July 2013 (it was only 3 spots in a cluster. I know thats weird for a first outbreak but I had NEVER had any sores before this.) I was diagnosed in August of 2013, after second outbreak (1 sore) by a swab test. I have been on daily suppressive therapy of 1gm/day since then and am still having frequent outbreaks. My dr. has decided something must be wrong with my immune system, which has me completely freaked out. I have taken 2 OraQuick tests, both with negative results. I am severely anemic and Vitamin D deficient and take medications for that. Are there ever instances where Valtrex doesn't work or could my other issues have something to do with my outbreaks?
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Avatar universal
Oh, and, never on both sides. Always ONLY on the left side.
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Avatar universal
They are in the genital region, on the outside of the upper area of left lip and yes, the exact same spot every time. Every time I have an ob it's only one sore and it does clear up quick. I had a swab test done in August 2013 and these sores look exactly like the one she tested and are in the same location as well.
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3149845 tn?1506627771
Where are you having the outbreaks and they most often occur in the same spot but not on both sides. How do you know these are herpes outbreaks?
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Avatar universal
I don't know which hsv I have, she never told me, but I will be asking when I go back. For a while, even on the Valtrex, I was having obs every 2 to 3 weeks. They would clear up quick and, they were rarely painful, but extremely annoying. I have been thinking about triggers. I do suffer from extreme, almost debilitating, anxiety and my life is very stressful. I have panic/anxiety attacks frequently so maybe that's what's causing my obs.
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3149845 tn?1506627771
Its just data. Different people have ob for different reasons so you might try to figure out what is triggering them. How often are you having them and do you have hsv2 or 1?
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Avatar universal
Bump.
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Avatar universal
My doctor had suggested trying 2gm/day, after my next round of blood work to check for other immune issues, since the 1gm/day doesn't seem to be very effective but she was concerned with the effect it would have on my liver.  When I have an outbreak, I do take 2gm/day for 3 days, then I go back to 1gm/day.  I'm just so confused as to why the 1gm/day suppression therapy wouldn't be effective if all the data says it should be.
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3149845 tn?1506627771
Hi for suppression and valtrex per terri warren it would be 1000mg once a day for those who have 10 or more ob per year and 500 mg for those of 9 or fewer. So since 1000 = 1 gram that would be correct.

You could also talk to your doctor about recurrent ob doses which is 2 grams twice in one day, 12 hours apart. Its not necessary to take it more than one day for the greatest benifit.
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