Why HSV IgM positive for one year

I tested Torch last year Apr planning for pregnancy. And the test result turns out to be:
CMV IgM+ IgG+
HSVI&II IgM+ IgG-

This year Mar, I tested again in the same hospital, the result is exactly the same as last year:
CMV IgM+ IgG+
HSVI&II IgM+ IgG-

Also, for double check, I redo the test in another hospital the same week I tested in 1st hospital.
CMV(DNA) <500 copies/mL, which in spec.
CMV IgM=0.22 which in spec of negative 250IU/mL
HSVI&II IgM+ IgG- (using trinity elisa)

Which test for CMV should I trust? And why the test result is different?
And for HSV, if I am infected, why after one year, my IgG still not show positive?

[catinbarefeet]

Hi saosaojianjian - according to these test results, you do not have herpes. The IgG tests are quite reliable, and after so many tests, you can probably trust the results. The IgM tests are fairly useless, as they can mistake other conditions for HSV, including chicken pox, mono, and shingles.

What I find curious is that the IgM (which generally indicates an early infection of a virus) has been positive every time. It's possible that your body is always fighting something like mono - or perhaps it's the CMV it's fighting. You might ask your doctor about the discrepancy.

I can't tell you which CMV test to trust, since I don't know enough about CMV testing. From what I've read, it's extremely common, not invasive, and tough to detect, however. Ask your doc to explain it, or even better, find some reliable medical, health, or research websites (such as the CDC or the NIH) to read up on it.

Best to you - I hope this helped somewhat!

[gracefromHHP]

some people will test + on igm testing for a lifetime.

your provider shouldn't be drawing the igm testing on you. the routine torch panel is really just meant to be used on newborns, not on adults. they should be specifically just ordering igg testing on you for cmv and herpes both if they feel the need for more testing. You are testing + for cmv which isn't unusual - most adults do pick it up during childhood and then it's not an issue during pregnancy.    so far you've not had proper herpes igg blood testing done - they've only done the non-type specific igg herpes testing which isn't accurate.

I really can't help a whole lot with testing for herpes in china. I recommend seeking out a local herpes support group for better help as to where to seek out proper testing for both you and your partner if you are trying to start a family.

grace

[saosaojianjian]

Thanks. I want to know why my HSV IgM always positive. It is because it is interact with mono or CMV? As I read up in this forum, there is no evidence that this is the case.

[saosaojianjian]

I asked the doctor, she told me the IgM test for HSV is not type specified, but the IgG is. She is also curious about why my IgM consistent positive but no IgG turns into positive. Do you know the reason? And my husband also took the test, his IgM&IgG all are negative.

[gracefromHHP]

you didn't post type specific igg herpes test results though.  the igg herpes results you posted were non-type specific.

we don't know why some folks are always + for herpes igm on blood testing. There are many issues with herpes igm blood testing which is why here in the US, the CDC has recommended it not be done on adults for the purpose of diagnosing herpes.