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hsv lab values
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hsv lab values

i had hsv 2 igg test done on 2/19/10 through lab corp, result was 1.52. the dr gave me valtrex and said i definatly had this, so i started the meds and decided to get recheched at a different lab, quest, and this time the result went up to 4.82, i know that result is supposedly a definate poitive, but what could make the result jump that high in 2 weeks? the other thing is, i was with my husband 11 years and he tested negative, when i left i was with someone 3 months and he also tested negative. i was with 2 people after my recent ex, both with protection and both 2 times. is it possible this is wrong? how can you be with someone so long and them not have it? i have never had an outbreak and was shocked by the results.
1 is it possible to be a carrier and not a passer?
2 is it possible the valtrex made the results go up?
3 2 weeks after taking the valtrex i stopped then started getting hives, is that a possible sign that could have made results jump?
my dr said the increase could have been a possible re infection, but i used protection.
im just hoping there is an explantion for the increase, and with the 2 different labs used.
and both my exs did have hsv 1
also before getting my test done i had not had sex since january
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55646_tn?1263664409
1.  It is possible to be a carrier and not a passer, yes.  
2.  No
3.  No.  The result value changes mostly in comparison to the control sample that is run at the same time.  Another reason your value could have changed so much is that you were newly infected, is that possible for you, that is, could you have been infected within the past few months?
There is no such thing as reinfection.  You might want to consider getting a herpes western blot through Quest to confirm those results.

Terri
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i wouldnt think this was new, so you tell me the chances here of getting it
was with my ex husband 11 years till oct 09
my ex bgf from nov to january 10th, the last month unprotected, hes negative
i had a partner on january 5th, one time protected
i had a partner on january 30th one time protected
was with my husband again on feb 4th one time protected
i was checked on 2/19 at 1.52 i had a new partner protected on 2/20 was with him 2 times before we split after the news, then checked on 3/5 at higher value.
now if i got it from the 2 partners in january which were time each protected and was with my husband again, wouldnt he have it
and what are the odds of contacting it while using protection?
also i forgot to mention, in 2002 i had an outbreak of blisters on my ear, the dr told me it was herpes and cultured it, the culture was neg but those older tests were not as accurate, is this possible?
so what else could make values rise if not a new infection?
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55646_tn?1263664409
I can see why you are confused.  Let me ask a few questions:
Were the partners on Jan 5, Jan 30, and Nov-Jan 10th all different people?
What is your HSV 1 status on the antibody test?
Condoms reduce the risk of herpes transmission by about 1/3.  
The value could have risen as a comparison to the control sample or because you have new infection, both as possible in your situation.

Terri
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Avatar_n_tn
yes all new partners, the one from nov to jan was one month unprotected, the other 2 were protected, the one from nov to january test was negative, and they did not check hsv 1.
i have never had an outbreak, once i thought maybe it was and it was cultured and came back neg, just happened to be irritation from soap i guess.
what do you mean by control sample? could 2 different labs have different values?
thanks!!
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Avatar_n_tn
well i wanted to post that i was checked again for hsv and test result came back as 1.39 and neg for hsv 1
so i guess with the 2 low reults and 1 high is it possible that i am negative?
and where do you get a biokit? is one better than the other of biokit and westerblot?
thanks
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55646_tn?1263664409
It is certainly possible that you are negative.  Yes, you need the western blot, and have it done 4 months from you last possible sexual exposure.  It must be frustrating to be on the edge like this, but sometimes clarification is required.

Terri
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Avatar_n_tn
hate to keep bothering you but i tried to post a couple questions over where its free and she told me to post them back here.
if someone is really positive with herpes would there result values stay high? since mine was low with lab corp and high with quest
what makes them fluctuate like that?
im just on edge waiting for the kit to arrive and my dr is no help is answering me
also are there std specialists you can go to and where can you find them?
thanks!
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55646_tn?1263664409
I"m really sorry, but I don't have any more clarifications than I did before.  I can't tell you why these result were so far apart.  I don't know where you live so I don't know where to direct you for further information.  Your best bet is to wait for the western blot kit and those results.

Terri
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Avatar_n_tn
sorry to bother you again, but a quick question about the WB, does anything you take interfere with the results? i have been getting hives since i quit taking the valtrex and stopped it about a month ago, dr gave me antihistamine for the hives, will this med or having hives interefere with getting the test done? thanks!
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55646_tn?1263664409
No,  nothing you take interferes with the western blot.

Terri
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Avatar_n_tn
i have had the western blot and awaiting my results but had to ask, i read on another post you commented that valtrex could have influenced the results. so could taking that med make a value increase? i had the 2 low ones without the valtrex and the high one when i was on the valtrex. i am just sitting here trying to be patient while still looking for answers. thanks so much
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Avatar_n_tn
Terri,

I need some help and advice from you. I was with a guy for about a year and always used a condom when we had sex except for a few times... and we only had sex a handful of times. After we ended he had sex with this girl and I found out she got HSV-2 from him. I found out that they hardly ever used a condom. I got tests done for chlamyida, gonorrhea, syphllis and HIV... all were negative but I did have a yeast infection. I got a blood test done for both herpes tests and I just got my blood test results and it came back positive. I've been reading  on the effect of yeast infections and herpes and that it could result in a false positive. This guy who possibly gave it to me never told me he had it and the other girl he was with said she had a yeast infection and the test came out positive but then she went and got re-tested and it came out negative. Honestly, what do you think? Do you think I have a good chance of getting it? I haven't had any symptoms of it and the only possible symptoms of herpes (the bumps and discharge) were folliculitis from shaving and the discharge was from the yeast infection. I am getting re-tested soon but wanted some advice. Thank you in advance for all of your help and support.
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55646_tn?1263664409
Valtrex, taken daily, could make someone infected look falsely negative on the test.  I think you are saying the opposite, if I am reading this correctly.

Terri
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55646_tn?1263664409
If the numeric value of the HSV 2 antibody test was greater than 3.5, then you are almost certainly truly infected.

Terri
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Avatar_n_tn
WB results came back today positive for HSV 1 and HSV 2,
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55646_tn?1263664409
You have clarification.  The WB is consistent with the ELISA results that you had previously.The western blot is more sensitive for HSV 1 than the ELISA test, which is likely why you were positive on both.  I believe that Dr. Handsfield's advice to you is sound and useful.  I know these aren't the results that you hoped for, but at least the testing is consistent for HSV 2.

Terri
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