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How long do beta blocker effects linger?

My BP was well-controlled on 100 mg Losartin and 7.5 mg Amlodipine, averaging around 125/68.

At peak exertion, during a treadmill stress test recently, my systolic BP reached 215. My cardiologist subbed 5 mg Nebivolol for the Amlodipine due to what he described as exercise-related hypertension. I took this medication for a week and experienced a range of unpleasant side effects, including exhaustion, significant depression and reduced heart rate (mid-60s, compared with my normal mid-80s).

I've been off the Nebivolol for five days, but I'm still experiencing these side effects. My heart rate has only come back to about 67-68.

Given the half-life of this drug and the fact that I only took it for a week, these side effects seem excessive.

Has anyone here had a similar experience? I see my cardiologist again on Tuesday, but in the meantime, I'm having a tough time concentrating at work and I'm very concerned.

Many thanks.
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Avatar universal
Hi there, The Beta Blockers do tend to have a re bound effect if stopped abruptly rather than gradually. A slower weening off helps but you may still get racing heart and other symptoms.

It should settle down over a couple of weeks at most.

I had a similar story on a much higher dose, and ended up stuck on a small dose every second day still!

All should be fine for you
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