I'm 39 female and for past 2 yrs have episodes of chest tightness, pain, & shortness of breath. Wt. 190lbs. Only happens during workouts and not always, 2-3 a month. Kickbox, spin & raquetball 4-5 days a week faithfully! Stress test/thallium, echo, ekgs and blood tests normal. Holter showed hr at 200 with pain episode. Have taken verapamil, toprol, atenolol, nadalol, stop due to side effects. Now on Cardizem la 180 mg daily + baby asprin for past month. Nothing has ended episodes. Friday did cardiopulmonary exercise stress test on treadmill. Start at 70 hr & 118/76 bp. Had to stop after 5 minutes due to short breath, but no pain. May sound odd, but I would like to have reached that point so that something may have been shown. Hr. 178 bp 178/72. Would this be a normal response even while taking Cardizem? Any other tests to consider? Any input is apreciated.