Medication Question

[pcmanic]

I take lamictal for a mood disorder. Is this med toxic to the kidneys? I'm at stage 3 and my gfr is 39.

[pcmanic]

Hi

I'll be seeing a nephrologist June 20th. My present Dr. (internal med.) said I don't need to watch my diet and that all my meds were okay. He also said I did not need to see a neph. untill my gfr was down to 15. I'm changing doctors. And I was wondering if hard work in a very hot factory is hard on my kidneys?

Thank You!

[Dr Smitha Mathews]

Hi,

lamictal is contraindictaed in patients with kidney disorders.

"Accumulation in Kidneys: Lamotrigine was found to accumulate in the kidney of the male rat, causing chronic progressive nephrosis, necrosis, and mineralization. These findings are attributed to α-2 microglobulin, a species- and sex-specific protein that has not been detected in humans or other animal species."
www.healthyplace.com/communities/bipolar/treatment/medications/lamictal_pi.asp

You will need to discuss the situation with your prescribing doctor and cease taking lamictal at the earliest.
Do keep us posted on your doubts and progress.

Regards