Recently diagnosed with Membranous Nephropathy after kidney biopsy. Supposed to be putting out 150mg/d of protein in urine and I am currently putting out 22,000mg/d of protein. Signs were: ankles swelling constantly making walking difficult, leg cramps when I wasn't swelling and foamy urine. Now that I have a diagnosis, I am on pill forms of Prednisone every other day and Cyclosporine 2x every day. I have been on the meds for over 1 1/2 weeks and noticed that the foamy urine amount has doubled, my face swells unbelievably, and walking is difficult, as the bottom of my feet and ankles cause me severe pain. I checked with my Nephrologist and she states that it will take a little while for my body to adjust to the medicine. Is anyone else having these side effects, and if so, how long did it take for your body to adjust to the medicine?