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Hi, Thin basement membrane disease (TBMD, also known as benignBenign ear cyst or tumor Benign positional vertigofamilialFamilial tremorhematuriaRbc - urine Urine - bloody and thin basement membrane nephropathy) is, along with IgA nephropathy, the most common cause of asymptomatic hematuria. The only abnormal finding in this disease is a thinning of the basement membrane of the glomeruli in the kidneys. Its importance lies in the fact that it has a benign prognosis, with patients maintaining a normal kidney function throughout their lives.
Overall, most people with thin basement membrane disease have an excellent prognosis. Some reports, however, suggest that a minority might develop hypertension. The high incidence of thin basement disease also means that it may be co-existing with other kidney diseases, such as diabetic nephropathy, which may have a not-so-benign prognosis.
Taken from website http://en.wikipedia.org/wiki/Thin_GBM_disease
In women, Alport syndrome disorder is usually mild, with minimal or no symptoms. In men, the symptoms are more severe and get worse faster.
For more information visit http://www.nlm.nih.gov/MEDLINEPLUS/ency/article/000504.htm
Overall, most people with thin basement membrane disease have an excellent prognosis. Some reports, however, suggest that a minority might develop hypertension. The high incidence of thin basement disease also means that it may be co-existing with other kidney diseases, such as diabetic nephropathy, which may have a not-so-benign prognosis.
Taken from website http://en.wikipedia.org/wiki/Thin_GBM_disease
In women, Alport syndrome disorder is usually mild, with minimal or no symptoms. In men, the symptoms are more severe and get worse faster.
For more information visit http://www.nlm.nih.gov/MEDLINEPLUS/ency/article/000504.htm