I agree with spoiler101, he should really be seen by a doctor and have a full work-up if he hasn't already. It sounds like he may have some pretty big swollen lymph nodes that might be pressing on some nerves, causing his face to feel dead. It's hard to say what it is he has, but his symptoms are very concerning, so I hope he is able to see a doctor soon.
It is hard to tell with so little to go on? Does someone go to the doctor's with him, to help explain some of his symptoms? He needs to first start off with a physical, & a complete CBC. Once his PC , then can go over his results, & maybe refer him to a specialist. You do not mention if he is active, or overweight, age, & etc. His doctor should have gone over his results, & ask him what might be his problem? Hope this helps some, & good luck!