I have had an enlarged spleen for 2 years now. All kinds of tests, hiv, hep c., mono, liver functions, cbcs, all were normal. But i feel bad, fatigue, loss of well being, depressed, itching on stomach, face and legs, abdominal paid around spleen. Is is possible i am in an early stage of lymphoma or leukemia and it is just not showing in my blood yet. I have no enlarged lymph nodes as I have had 2 ct scans, and a liver/spleen scan, showing only the enlarged spleen of 14cm. Any answers would be appreciated.