Is myelodysplasia genetic?

My mom passed away 2 months after being diagnosed with AML which had evolved from myelodysplasia.  Of course I am paranoid due to some recent bloodwork I have gotten this year.  Please let me know if you think I should investigate this further or stop worrying.  Thank you so much.
CO2      31
ALK PHOS Total     49
WBC  4.1
RBC   3.83
HGB   11.8
HCT     35.1
I am always tired and I have noticed over the last few weeks that it doesnt take much to bruise myself.  I am 54 years old with rheumatoid arthritis and fibromyalgia.  Could the Methotrexate be causing this blood level?
Thank you for your input.

[PaulMD]

Hi there.

Methotrexate can really have hematologic side effects, and your blood picture is consistent with such side effects.  The drug primarily affects the white and red cells that can give rise to low levels of these.  I suggest that you continue with your treatment, continue the blood work up monitoring and not to think so much about myelodysplastic diseases as we really have no concrete evidence of this being inherited (only less than 10% of cases).