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LDH level of 896 in child age 2 ???? what could this mean

this has been going on for 18 months.. LDH is the only blood test he has had thats been abnormal... & now its at the highest ever..  896 .
his symptoms are reoccuring episodes of malaise & lethargy...sits around many days unable to really do much normal toddler activty saying he's tired & his legs hurt a bit... His lymph nodes in his neck (cervical) & nodes at base of his head enlarge & then decrease all the time (but are ALWAYS prominent even on a good period). We are desperate for any advice
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1233038 tn?1267671355
Hi,
I have no idea what this LDH level is but have they tested him for anything rheumatoid. I have a 2 year old whom has been sick for over a year with mulitple infections and they did blood tests that showed a pos ana and his smith antibody was also high. They think he has lupus of Juvenil Rhematoid Artheritis. Your son's symptoms could be results of JRA. Look these diseases up and see if he has the symptoms and if so ask about it. My son always has a really high WBC but only when hes sick. His sed rate is always extremely high which shows he has inflammation in his body and that is why he complaind with pain and mostly in his knees and stomach for my son but tis different with every child. When hes sick he does not want to do anything but lay on the couh. I know they did the C3 and C4 on my son and his was normal too. With these rheumatoid diseases he can be negative but  others can be positive its very confusing. I do not know anything about the blood work you talk about so i migth be in left field but it cant hurt to check it out on the internet. good luck to you
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Avatar universal
have you thought about jeuvenile dermatomyositis?
might not present with the skin rash but children find it hard to get up off the floor or climb stairs, often complaining that their legs hurt. would get a raised LDH level.
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Avatar universal
Thank you so much for your response... I have a question for you... Is it possible for my child to have a completly normal Blood count but still have lymphoma or Leukemia? The infectious diseases consultant says with my sons full blood count being so normal & the boood film not showing any abnormal cells.. means there is no way he could have it ?? Please could you comment on this??
He also feels the level of LDH being 896 is not too bad as the lab said anything up to 920 is normal (however in other labs they say only up to 490 is normal?)

I was also lookin again at his test results.... His CH 100 total Compliment level was very raised at 1200 - but compents C3 & C4 were normal??
His IGE is massivly raised at 600 (normal should be under 32)
His Albumin levels are slighty raised too.

I really hope you can answer these questions for me.. Thanks again

Joanne
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Avatar universal
Hi there.

Increase in LDH level is a sign of a proliferative disease, meaning that cells in the body (mostly the blood cells) are undergoing proliferation and rapid turn over.  These can be seen in cases of blood malignancies like leukemia, and solid tumors such as lymphoma.  I suggest that you have the lymph nodes evaluated and possibly undergo a biopsy procedure to rule out these conditions.  If ever diagnosed with lymphoma or leukemia, chemotherapy may be warranted.  Lymphoma and leukemia are curable childhood diseases.

Regards.
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